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吕全军, 崔晗, 田亚兰, 李倩文, 薄亚聪, 朱艺伟, 游杰, 崔玲玲. 中国人群进食快对食管癌发病影响meta分析[J]. 中国公共卫生, 2018, 34(4): 584-588. DOI: 10.11847/zgggws1115106
引用本文: 吕全军, 崔晗, 田亚兰, 李倩文, 薄亚聪, 朱艺伟, 游杰, 崔玲玲. 中国人群进食快对食管癌发病影响meta分析[J]. 中国公共卫生, 2018, 34(4): 584-588. DOI: 10.11847/zgggws1115106
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Quan-jun LÜ, Han CUI, Ya-lan TIAN, . Association between eating fast and risk of esophageal cancer in Chinese population: a meta-analysis[J]. Chinese Journal of Public Health, 2018, 34(4): 584-588. DOI: 10.11847/zgggws1115106
Citation: Quan-jun LÜ, Han CUI, Ya-lan TIAN, . Association between eating fast and risk of esophageal cancer in Chinese population: a meta-analysis[J]. Chinese Journal of Public Health, 2018, 34(4): 584-588. DOI: 10.11847/zgggws1115106
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中国人群进食快对食管癌发病影响meta分析

Association between eating fast and risk of esophageal cancer in Chinese population: a meta-analysis

    摘要
  • 摘要:
      目的   探讨中国人群进食快对食管癌发病的影响，为食管癌的预防提供科学依据。
      方法   检索中国知网数据库、万方数据库、PubMed数据库和Web of Science数据库，并辅以手工检索和文献追溯法收集1980年1月 —2017年2月公开发表的有关进食快与食管癌关系的相关文献；应用Stata 11.0软件对纳入的文献进行meta分析。
      结果   最终纳入26篇文献（中文文献22篇，英文文献4篇），均为病例对照研究，累计病例组8 418例，对照组11 710例；Meta分析结果显示，中国人群进食快者食管癌的发病风险为非进食快者的2.518倍（OR = 2.518，95 % CI = 2.024～3.131）；亚组分析结果显示，在不同地区、不同对照来源、不同发表年份、不同文献来源中进食快者食管癌发病风险均高于非进食快者（均P < 0.01）；敏感性分析和发表偏倚检验结果显示，本次meta分析纳入的文献不存在发表偏倚，结果较为稳定。
      结论   进食快会增加中国人群中食管癌的发病风险。

     

    Abstract:
      Objective  To evaluate the influence of easting fast on esophageal cancer incidence in Chinese population, and to provide evidences for prevention of esophageal cancer.
      Methods   We searched the China National Knowledge Infrastructure (CNKI), WanFang Database, PubMed and Web of Science for all relevant studies published from January 1980 through February 2017 in English or in Chinese. Stata 11.0 software was used for the meta-analysis.
      Results   A total of 26 studies were included in this analysis, involving 8 418 esophageal cancer cases and 11 710 controls. All the studies were case-control studies. The overall random effect odds radio (OR) of esophageal cancer and its 95% confidence interval (CI) for eating fast were 2.518 (2.024 – 3.131) in comparison with not eating fast. Subgroup analysis found that eating fast was associated with an increased risk of esophageal cancer compared to not eating fast among the participants of the studies published in different years and in various jornals (P < 0.01 for all). The results of sensitivity analysis and publication bias test showed that all the studies retrieved were good in stability and there was no publication bias.
      Conclusion   The results suggest that eating fast can increase the risk of esophageal cancer in Chinese population.

     

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