Objective  To examine the prevalence and risk factors of psoriasis among rural minority residents in Qiannan prefecture of Guizhou province (Qiannan) and to provide evidences for developing relevant interventions.

  Methods  A total of 99 876 minority rural permanent residents (≥20 years old) were selected with cluster random sampling from Qiannan and surveyed with a face-to-face interview, physical examination, and laboratory tests between January 2016 and October 2017.

  Results  Among the participants, totally 1 239 psoriasis cases were diagnosed, with a prevalence rate of 1.24% and a standardized prevalence rate of 1.21%. Multivariate unconditional logistic regression revealed risk factors of psoriasis as following: Buyi nationality (odds ratioOR= 3.411, 95% confidence interval 95% CI: 1.635 – 5.195), family history of psoriasis (OR = 3.415, 95% CI: 1.321 – 5.879), overweight/obesity (OR = 2.933, 95% CI: 1.225 – 3.459), smoking (OR = 3.215, 95% CI: 1.265 – 5.123), preference for salty food (OR = 3.901, 95% CI: 1.431 – 4.706), preference for eating chili (OR = 2.867, 95% CI: 1.245 – 3.782), preference for fish/shrimp food (OR = 3.157, 95% CI: 1.339 – 5.182), long-term stress or anxiety (OR = 2.511, 95% CI: 1.142 – 2.998), and living in a slate house (OR = 3.483, 95% CI: 1.335 – 4.792).

  Conclusion  The prevalence rate of psoriasis is relatively high among rural minority adults in Qiannan region of Guizhou province and interventions on risk factors of the disease should be carried out in the population.