北京市18～79岁居民不良睡眠状况与慢性病共病患病关系

隗瑛琦; 马爱娟; 谢瑾; 方凯; 董晶; 谢晨; 董忠

doi:10.11847/zgggws1136854

北京市18～79岁居民不良睡眠状况与慢性病共病患病关系

doi: 10.11847/zgggws1136854

北京市疾病预防控制中心慢性病预防与控制所，北京 100013

详细信息

作者简介:
隗瑛琦（1986 – ），女，北京人，助理研究员，博士，主要从事慢性病预防与控制工作

通讯作者:
董忠，E-mail：dongzhongcdcmb@yeah.net

中图分类号: R 195.4
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- 文章访问数: 195
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- 被引次数: 0
出版历程
- 接收日期: 2021-09-10
- 网络出版日期: 2022-09-17
- 刊出日期: 2022-11-30

Association of poor sleep with multiple chronic conditions among adult residents in Beijing: a cross-sectional survey

Department of Non-communicable Chronic Disease Control and Prevention, Beijing Center for Disease Prevention and Control, Beijing 100013, China

摘要

摘要: 目的了解北京市18～79岁居民不良睡眠状况与慢性病共病患病的关系，为慢性病共病的预防控制提供参考依据。方法于2017年8 — 12月采用多阶段分层整群随机抽样方法在北京市16个区抽取13 240名18～79岁常住居民进行问卷调查、体格检查和实验室检测；采用复杂抽样加权方法估计居民不良睡眠率和慢性病共病患病率，并应用多因素非条件logistic回归模型分析打鼾/窒息、中间觉醒 ≥ 2次、早醒、入睡困难、服用安眠药5种不良睡眠状况与慢性病共病患病的关系。结果北京市13 240名18～79岁居民中，自述30 d内每周 ≥ 3 d出现打鼾/窒息3413人（25.8 %）、入睡困难2536人（19.2 %）、中间觉醒 ≥ 2次3103人（23.4 %）、早醒2671人（20.2 %）、服用安眠药367人（2.8 %），有 ≥ 1种不良睡眠状况者6490人，复杂抽样加权后不良睡眠率为52.1 %；慢性病共病患病者4 980例，复杂抽样加权后慢性病共病患病率为41.7 %；在调整了性别、年龄、文化程度、婚姻状况、居住地、是否现在吸烟、近7 d是否饮酒、是否身体活动不足、是否主动体检和是否健康体重等混杂因素后，多因素非条件logistic回归分析结果显示，打鼾/窒息（OR = 1.955，95 % CI = 1.731～2.208）、中间觉醒 ≥ 2次（OR = 1.914，95 % CI = 1.591～2.202）、早醒（OR = 1.802，95 % CI = 1.534～2.117）、入睡困难（OR = 1.625，95 % CI = 1.380～1.913）、服用安眠药（OR = 2.617，95 % CI = 1.907～3.592）这5种不良睡眠状况均与北京市18～79岁居民慢性病共病的风险有关。结论北京市18～79岁居民不良睡眠和慢性病共病患病状况均较为严重，且多种不良睡眠状况均与慢性病共病患病有关,应在治疗已有疾病的同时关注患者的睡眠问题。
- 慢性病共病 /
- 患病 /
- 不良睡眠状况 /
- 关系
Abstract: Objective To analyze the relationship between poor sleep and multiple chronic conditions (MCC) among residents aged 18 – 79 years in Beijing in 2017 for providing reference to the prevention and control of chronic disease comorbidity. Methods A total of 13 240 permanent residents aged 18 – 79 years were recruited from 16 districts of Beijing municipality with stratified multistage cluster sampling. Face-to-face questionnaire interviews, physical examination and laboratory detections were conducted among the residents during August – December 2017. Complex sampling weighting method was used to estimate the prevalence of poor sleep status and MCC and correlations between poor sleep status and MCC were analyzed with unconditional multivariate logistic regression models. Results All the residents completed the survey. The self-reported prevalence rate of poor sleep status at least three days in a week during past 30 days was 25.8% (n = 3 413) for snoring / sleep apnea, 19.2% (n = 2 536) for difficulty in falling asleep, 23.4% (n = 3 103) for two and more times of intermediate awakening in one night, 20.2% (n = 2 671) for early awakening, and 2.8% (n = 367) for taking sleeping pills; the complex sampling weighted prevalence rate of poor sleep (reporting one or more bad sleep conditions) was 52.1% (n = 6 490). Totally 4 980 sufferers of MCC were identified among all the participants, with a weighted MCC prevalence rate of 41.7%. Unconditional multivariate logistic regression analysis revealed that the participants reporting the poor sleep status were associated with MCC, with the odds ratios (95% confidence intervals) of 1.955 (1.731 – 2.208) for the participants reporting snoring / sleep apnea, 1.914 (1.591 – 2.202) for intermediate awakening of ≥ two times, 1.802 (1.534 – 2.117) for early awakening, 1.625 (1.380 – 1.913) for difficulty in falling asleep, and 2.617 (1.907 – 3.592) for taking sleeping pills after adjusting for confounding factors such as gender, age, education, marital status, place of residence, smoking, alcohol drinking during past 7 days, physical activity, active physical examination and body weight. Conclusion Poor sleep status and MCC were prevalent and a variety of poor sleep conditions were related to MCC among 18 – 79 years old residents in Beijing.
- multiple chronic conditions /
- prevalence /
- poor sleep status /
- correlation

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表 1 北京市不同特征18～79岁居民慢性病共病患病情况比较

特征		调查数	慢性病共病患病数	慢性病共病患病率（%） ^b	χ²值	P 值
性别	男性	6164	2408	43.4	13.436	0.001
	女性	7076	2572	38.2
年龄（岁）	18～44	6671	1332	22.6	347.699	< 0.001
	45～59	4014	1941	47.0
	60～79	2555	1706	67.4
文化程度 ^a	小学及以下	1246	649	50.9	21.387	< 0.001
	初中/中专/高中	8080	3307	43.5
	大专及以上	3895	1018	33.8
婚姻状况 ^a	非在婚	3002	676	26.3	98.735	< 0.001
	在婚	10195	4298	44.8
居住地	城区	8664	3310	41.7	0.009	0.926
	郊区	4576	1670	41.5
是否现在吸烟 ^a	否	9923	3637	40.7	3.711	0.061
	是	3286	1327	43.6
是否近7 d内饮酒	否	10564	3776	39.6	53.379	< 0.001
	是	2676	1204	47.0
是否身体活动不足	否	5637	1953	39.9	6.298	0.016
	是	7603	3027	43.2
是否主动体检 ^a	否	3776	1307		2.697	0.108
	是	9445	3671	42.7
是否健康体重 ^a	否	8601	3783	47.5	119.805	< 0.001
	是	4618	1191	29.8
是否打鼾/窒息 ^a	否	9808	3119	35.4	301.617	< 0.001
	是	3413	1852	56.1
是否入睡困难 ^a	否	10691	3626	38.5	56.656	< 0.001
	是	2536	1351	55.4
是否中间觉醒 ≥ 2次 ^a	否	10121	3285	36.5	141.318	< 0.001
	是	3103	1690	57.5
是否早醒 ^a	否	10556	3592	38.4	70.850	< 0.001
	是	2671	1385	54.5
是否服用安眠药 ^a	否	12860	4722	40.6	92.043	< 0.001
	是	367	254	74.2
注：a 数据有缺失；b 复杂抽样加权后患病率。

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