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冯石献, 王国杰, 田惠子, 刘建涛, 王梦微, 杨国俊, 高莉. 河南省成年人秋冬季维生素D缺乏患病情况调查[J]. 中国公共卫生, 2022, 38(11): 1450-1454. DOI: 10.11847/zgggws1137307
引用本文: 冯石献, 王国杰, 田惠子, 刘建涛, 王梦微, 杨国俊, 高莉. 河南省成年人秋冬季维生素D缺乏患病情况调查[J]. 中国公共卫生, 2022, 38(11): 1450-1454. DOI: 10.11847/zgggws1137307
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FENG Shi-xian, WANG Guo-jie, TIAN Hui-zi, . Prevalence of vitamin D deficiency during autumn and winter among adults in Henan province[J]. Chinese Journal of Public Health, 2022, 38(11): 1450-1454. DOI: 10.11847/zgggws1137307
Citation: FENG Shi-xian, WANG Guo-jie, TIAN Hui-zi, . Prevalence of vitamin D deficiency during autumn and winter among adults in Henan province[J]. Chinese Journal of Public Health, 2022, 38(11): 1450-1454. DOI: 10.11847/zgggws1137307
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河南省成年人秋冬季维生素D缺乏患病情况调查

Prevalence of vitamin D deficiency during autumn and winter among adults in Henan province

    摘要
  • 摘要:
      目的  了解河南省成年人维生素D缺乏（VDD）情况，为减少VDD带来的健康损害提供参考。
      方法   于2018年10月— 2019年2月，采用多阶段整群随机抽样方法选择8 455名调查对象，对抽取的调查对象检测血清25羟基维生素D，应用复杂抽样加权调整方法，对河南省成年人秋冬季VDD患病率（PVDD)进行估算。
      结果  估算的河南省成年居民PVDD为24.2 %（95 % CI = 19.5 %～29.6 %），男性PVDD为16.0 %，低于女性的32.0 %；在各年龄组中，18～39岁年龄组PVDD最高，为29.6 %；单身人群PVDD为37.2 %，高于非单身人群的22.2 %，差异均有统计学意义（均P＜0.05）。多因素对数二项分布回归分析结果显示，河南省成人VDD与性别、婚姻状态、职业、文化程度、检查季节有关，以男性为参照，女性校正现患比（APR）及其95 % CI为2.04（1.56 ~ 2.68）；以非单身为参照，单身人群APR（95 % CI）为1.29（1.01 ~ 1.64）；以农林牧渔水业为参照，农林牧渔水业以外行业、无工作/家务、退休的人群APR（95 % CI）分别为1.81（1.27～2.58）、1.56（1.05～2.30）、1.76（1.22～2.54）；以小学及以下文化程度为参照，初中、高中/中专/技校、大专及以上人群APR（95 % CI）分别为1.33（0.99～1.80）、1.44（1.03～2.03）、1.78（1.32～2.40）；以秋季为参照，冬季APR（95 % CI）为1.44（1.14～1.82）。
      结论   河南省成年人秋冬季PVDD较高；女性、单身、较高文化程度、农林牧渔水业以外行业、冬季增加了VDD患病风险。

     

    Abstract:
      Objective  To examine the status of vitamin D deficiency (VDD) during the autumn and winter among adults in Henan province and to provide references for reducing adverse health effect of VDD.
      Methods  Using multistage cluster random sampling, we conducted a survey among 8 455 urban and rural residents aged 18 years and above in 14 districts/counties of Henan province from October 2018 through February 2019. The participants′ serum 25(OH)D2 and 25(OH)D3 were determined with high-performance liquid chromatography-tandem mass spectrometry. Complex sampling weighting adjustment was adopted to estimate the prevalence of VDD (PVDD) among the participants.
      Results  The estimated PVDD for all participants was 24.2% (95% confidence interval 95% CI: 19.5% – 29.6%); the PVDD for the males was significantly lower than that for the females (16.0% vs. 32.0%, P < 0.05); the age-specific PVDD was highest (29.6%) for the participants aged 18 – 39 years; and the unmarried participants had significantly higher PVDD compared to those married (37.2% vs. 22.2%, P < 0.05). Multivariate log binomial regression analysis showed that in comparison with control groups, the adjusted prevalence ratio (APR) of VDD was significantly higher in following subgroups: females (vs. males: 2.04, 95% CI: 1.56 – 2.68), the unmarried (vs. the married: 1.29, 95% CI: 1.01 – 1.64), being employed in industries other than agriculture/forestry/animal husbandry/fishery/aquaculture (vs. being employed in the industries listed above or the unemployed: 1.81, 95% CI: 1.27 – 2.58; vs. the employed/housekeepers: 1.56, 95% CI: 1.05 – 2.30; vs. retirees: 1.76, 95% CI: 1.22 – 2.54), with higher education attainment (vs. primary school and below: 1.33 95% CI: 0.99 – 1.80 for those with junior high school attainment, 1.44 95% CI: 1.03 – 2.03 for senior high /technical secondary / technical school, and 1.78 95% CI: 1.32 – 2.40 for college and above), being surveyed in winter season (vs. in autumn season: 1.44, 95% CI: 1.14 – 1.82 ).
      Conclusion  The prevalence of vitamin D deficiency is high during the autumn and winter season among adults in Henan province and the prevalence was mainly influenced by gender, marital status, education attainment, occupation, and season.

     

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