Disease burden of anxiety disorders in China in 1990 and 2019: a comparative analysis among global regions with different sociodemographic index
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摘要:
目的 比较1990年和2019年中国与世界不同社会人口学指数(SDI)地区居民焦虑症疾病负担变化趋势,为合理配置卫生资源以及制定焦虑症预防控制策略提供参考依据。 方法 基于2019年全球疾病负担(GBD 2019)研究数据,采用发病数、伤残损失寿命年(YLDs)、标化发病率、标化患病率和标化YLD率等指标比较1990年和2019年中国与世界不同SDI地区居民焦虑症疾病负担情况及其变化趋势。 结果 中国居民2019年焦虑症的发病数和YLDs分别为7285634例和4574328人年,较1990年焦虑症发病数和YLDs的6667495例和4045138人年增加了9.37 %和13.08 %。与世界不同SDI地区居民比较,1990年和2019年中国居民焦虑症标化发病率、标化患病率、标化YLD率均处于较低水平且呈下降趋势,其中标化发病率由1990年的556.56/10万下降至2019年的522.97/10万,变化率为 − 6.03 %,标化患病率由1990年的3507.31/10万下降至2019年的3164.18/10万,变化率为 − 9.78 %,标化YLD率由1990年的337.47/10万下降至2019年的306.02/10万,变化率为 − 9.32 %;而高SDI地区居民焦虑症标化发病率、标化患病率、标化YLD率均处于较高水平且呈增长趋势,分别由1990年的679.46/10万、4637.21/10万和441.19/10万上升至2019年的710.54/10万、4806.55/10万和456.89/10万,变化率分别为4.57 %、3.65 %和3.56 %。1990年和2019年中国与世界不同SDI地区女性居民焦虑症疾病负担均远高于男性居民,2019年中国和高SDI地区女性居民焦虑症标化发病率、标化患病率、标化YLD率分别为630.04/10万和837.43/10万、3912.33/10万和6168.67/10万、377.20/10万和582.82/10万,均高于男性居民的426.33/10万和591.16/10万、2453.91/10万和3482.78/10万、238.88/10万和334.80/10万。 结论 1990年和2019年中国居民与世界不同SDI地区居民相比焦虑症疾病负担降幅最大,高SDI地区焦虑症疾病负担形势较为严峻;中国与世界不同SDI地区女性居民仍占焦虑症疾病负担的主导地位。 Abstract:Objective To compare the trend in disease burden of anxiety disorders between China and global regions with different socio-demographic index (SDI) in 1990 and 2019 for providing evidence to rational allocation of health resources and formulation of anxiety prevention and control strategies. Methods The study data were from the Global Burden of Disease Study (GBD 2019). Incidence, years lived with disability (YLDs), age-standardized incidence, age-standardized prevalence, and age-standardized YLDs rate were applied to compare the disease burden of anxiety disorders and its changing trend among residents in China to those of residents in global regions with different SDI in 1990 and 2019. Results Among Chinese residents, the incidence number and YLDs of anxiety disorders increased from 6 667 495 and 4 045 138 person-years in 1990 to 7 285 634 and 4 574 328 person-years in 2019, with the increase rates of 9.37% and 13.08%, respectively. Compared with those in the residents of global regions with different SDI, the age-standardized incidence rate, age-standardized prevalence rate, and age-standardized YLDs rate of anxiety disorders in China in 1990 and 2019 were all at low levels and showed decreasing trend; the age-standardized incidence rate decreased from 556.56/100 000 to 522.97/100000, with a change rate of − 6.03%; the age-standardized prevalence rate decreased from 3507.31/100 000 to 3 164.18/ 100 000, with a change rate of − 9.78%; the age-standardized YLDs rate decreased from 337.47/100000 to 306.02 /100000, with a change rate of − 9.32%. In contrast, the age-standardized incidence rate, age-standardized prevalence rate, and age-standardized YLDs rate of anxiety disorders among populations in the global regions with high SDI were all at high levels and increased from 679.46/100 000, 4637.21/100 000, and 441.19/100 000 in 1990 to 710.54/100 000, 4 806.55/100 000 and 456.89/100 000 in 2019, with the changing rates of 4.57%, 3.65%, and 3.56%. In 1990 and 2019, the burden of anxiety disorders in female residents in China and in global regions with different SDI were much higher than that in male residents. In comparison with those in the males, higher age-standardized rates (for 100 000 population) were observed in the females in China and in global regions with high SDI when examining anxiety disorders′ incidence (630.04 vs. 425.33 and 837.43 vs. 591.16), prevalence (3 912.33 vs. 2 453.91 and 6 168.67 vs. 3 482.78), and YLDs (377.20 vs. 238.88 and 582.82 vs. 334.80). Conclusion Compared with the residents in global regions with different SDI, the disease burden of anxiety disorders among Chinese residents decreased greatly from 1990 to 2019 and the disease burden was heavier in the female populations than in the male populations both in China and in global regions with different SDI. -
Key words:
- anxiety disorder /
- disease burden /
- variation tendency /
- China /
- socio-demographic index /
- region /
- comparison
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表 1 1990年和2019年中国与世界不同SDI地区总人群焦虑症疾病负担及其变化趋势比较
国家与地区 标化发病率(1/10万) 标化患病率(1/10万) 标化YLDs率(1/10万) 1990年 2019年 变化率(%) 1990年 2019年 变化率(%) 1990年 2019年 变化率(%) 中国 556.56 522.97 − 6.03 3507.31 3164.18 − 9.78 337.47 306.02 − 9.32 低SDI地区 542.05 556.08 2.59 3402.28 3494.81 2.72 320.60 331.48 3.39 中低SDI地区 538.33 549.87 2.14 3385.00 3470.02 2.51 319.46 328.89 2.95 中SDI地区 583.58 599.21 2.68 3726.18 3793.62 1.81 356.01 363.15 2.01 中高SDI地区 581.29 584.85 0.61 3789.52 3754.47 − 0.92 362.07 359.98 − 0.58 高SDI地区 679.46 710.54 4.57 4637.21 4806.55 3.65 441.19 456.89 3.56 表 2 1990年和2019年中国与世界不同SDI地区男性人群焦虑症疾病负担及其变化趋势比较
国家与地区 标化发病率(1/10万) 标化患病率(1/10万) 标化YLD率(1/10万) 1990年 2019年 变化率(%) 1990年 2019年 变化率(%) 1990年 2019年 变化率(%) 中国 453.70 426.33 − 6.03 2684.11 2453.91 − 8.58 260.71 238.88 − 8.38 低SDI地区 477.11 491.63 3.04 2792.57 2880.97 3.17 265.62 275.84 3.85 中低SDI地区 459.10 468.08 1.96 2668.02 2707.41 1.48 254.35 259.15 1.89 中SDI地区 486.13 496.21 2.07 2879.28 2895.51 0.56 277.74 279.64 0.68 中高SDI地区 463.45 469.78 1.37 2701.39 2706.94 0.21 260.51 261.96 0.56 高SDI地区 558.38 591.16 5.87 3300.72 3482.78 5.52 317.65 334.80 5.40 表 3 1990年和2019年中国与世界不同SDI地区女性人群焦虑症疾病负担及其变化趋势比较
国家与地区 标化发病率(1/10万) 标化患病率(1/10万) 标化YLD率(1/10万) 1990年 2019年 变化率(%) 1990年 2019年 变化率(%) 1990年 2019年 变化率(%) 中国 667.55 630.04 − 5.62 4361.09 3912.33 − 10.29 417.48 377.20 − 9.65 低SDI地区 607.56 620.63 2.15 4014.96 4099.62 2.11 375.87 386.37 2.79 中低SDI地区 620.59 633.42 2.07 4123.53 4225.53 2.47 386.58 398.15 2.99 中SDI地区 685.16 706.31 3.09 4586.37 4694.31 2.35 435.70 447.18 2.63 中高SDI地区 703.06 707.59 0.64 4840.83 4812.84 − 0.58 460.75 459.48 − 0.28 高SDI地区 805.24 837.43 4.00 5945.72 6168.67 3.75 562.65 582.82 3.58 -
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