Prevalence and associates of metabolic syndrome among adult residents in Yunnan province, 2021
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摘要:
目的 了解云南省成年居民代谢综合征（MS）的患病现状及其影响因素，为采取有针对性的MS防控及干预措施提供参考依据。 方法 于2021年1 — 12月采用多阶段分层随机抽样方法在云南省8个县（区）抽取9600名 ≥ 18岁成年常住居民进行问卷调查、体格检查和实验室检测。 结果 云南省有效调查的7396名成年居民中，MS患者1210例，MS患病率为16.4%；多因素非条件logistic回归分析结果显示，年龄 ≥ 35岁、有高血压家族史和体质指数（BMI） ≥ 24.0是云南省成年居民MS患病的危险因素，女性是云南省成年居民MS患病的保护因素；MS不同异常组分聚集模式中，云南省成年居民最常见的代谢异常组合为“中心性肥胖 + 血压异常 + 高甘油三酯（TG）”，为397例，患病率为5.37%。 结论 云南省成年居民MS患病率较高，中老年男性、超重肥胖和有高血压家族史居民为该地区MS防控的重点人群。 Abstract:Objective To investigate the prevalence of metabolic syndrome (MS) and its associated factors among adult residents in Yunnan province, and to provide a reference for the adoption of targeted MS prevention and control measures. Methods Face-to-face interview with a questionnaire developed by National Center for Cardiovascular Diseases, physical examination and laboratory tests were conducted among 9 600 adult permanent residents ( ≥ 18 years of age) recruited in 8 counties (districts) of Yunnan province with stratified multistage random sampling during 2021. Results Of the 7 396 participants surveyed effectively, 1 210 (16.4%) were assessed as suffering from MS. Multivariate logistic regression analysis showed that age ≥ 35 years old, family history of hypertension and with a body mass index (BMI) of ≥ 24.0 were risk factors for MS; while, female gender was a protective factor for MS. Among different aggregation patterns for abnormal components of MS, the most common combination of metabolic abnormalities detected among the participants was “abdominal obesity + elevated blood pressure + high triglycerides”. Conclusion MS is prevalent seriously among adult residents in Yunnan province. Middle-aged and elderly men, persons being overweight or obese, and people with family history of hypertension should be considered as high-risk groups in MS prevention and control. -
Key words:
- metabolic syndrome /
- prevalence /
- influencing factor /
- adult residents
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表 1 云南省不同特征成年居民MS患病情况比较
特征 调查人数 MS患病例数 MS患病率（%） χ2 值 P 值 性别 男性 3612 735 20.3 82.081 < 0.001 女性 3784 475 12.6 年龄（岁） 18～34 2543 168 6.6 324.632 a < 0.001 35～44 1472 230 15.6 45～54 1271 262 20.6 55～64 883 217 24.6 ≥ 65 1227 333 27.1 民族 汉族 5072 836 16.5 0.177 0.674 少数民族 2324 374 16.1 文化程度 小学及以下 2458 556 22.6 105.427 < 0.001 初中及以上 4938 654 13.2 人均可支配收入（万元） ≤ 3 4793 821 17.1 5.885 0.015 > 3 2603 389 14.9 居住地 城市 4000 685 17.1 3.724 0.054 农村 3396 525 15.5 吸烟情况 不吸烟 5552 854 15.4 15.577 < 0.001 吸烟 1844 356 19.3 饮酒情况 不饮酒 6200 954 15.4 26.532 <0.001 饮酒 1196 256 21.4 体力活动情况 不足 4367 725 16.6 0.455 0.500 充足 3029 485 16.0 有无高血压家族史b 无 4873 701 14.4 27.883 < 0.001 有 2089 406 19.4 有无糖尿病家族史b 无 6558 1024 15.6 9.353 0.002 有 424 90 21.2 BMI < 24.0 4014 159 4.0 1374.078 < 0.001 24.0～27.9 2385 548 23.0 ≥ 28.0 997 503 50.5 注：a 采用趋势性χ2检验；b 数据有缺失。 
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表 2 云南省成年居民MS患病影响因素多因素非条件logistic回归分析
因素 参照组 比较组 β $S_{\bar x}$ Wald χ2 值 P 值 OR 值 95%CI 性别 女性 男性 − 0.655 0.078 71.160 < 0.001 0.520 0.446～0.605 年龄（岁） 35～44 18～34 0.683 0.120 32.359 < 0.001 1.981 1.565～2.506 45～54 1.032 0.120 73.421 < 0.001 2.807 2.217～3.554 55～64 1.439 0.130 122.887 < 0.001 4.215 3.268～5.435 ≥ 65 1.854 0.124 223.226 < 0.001 6.386 5.008～8.145 有无高血压家族史 有 无 0.285 0.082 11.899 0.001 1.329 1.131～1.562 BMI 24.0～27.9 < 24.0 1.908 0.104 338.185 < 0.001 6.738 5.499～8.258 ≥ 28.0 3.304 0.114 842.757 < 0.001 27.208 21.769～34.006
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表 3 云南省成年居民MS不同异常组分聚集模式
MS组合
种类（种）中心性
肥胖血压
异常血糖
异常高TG 低HDL-C 患病数 患病率（%） 3 + + + – – 105 1.42 3 + + – + – 397 5.37 3 + + – – + 43 0.58 3 – + + + – 126 1.70 3 – + + – + 19 0.26 3 – – + + + 18 0.24 3 + – + – + 11 0.15 3 + – – + + 39 0.53 3 – + – + + 79 1.07 3 + – + + – 19 0.26 4 + + + – + 17 0.23 4 + – + + + 18 0.24 4 – + + + + 58 0.78 4 + + – + + 72 0.97 4 + + + + – 130 1.76 5 + + + + + 59 0.80 注：“ + ”表示存在该项代谢异常组分，“–”表示不存在该项代谢异常组分。
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