黑龙江省2018年急性胃肠炎发病情况及其疾病负担分析

高飞; 张剑峰; 李敬晶; 王佳玉; 张歆; 刘忠卫

doi:10.11847/zgggws1138765

黑龙江省2018年急性胃肠炎发病情况及其疾病负担分析

doi: 10.11847/zgggws1138765

1.
黑龙江省疾病预防控制中心，哈尔滨 150036
2.
哈尔滨医科大学

基金项目: 科技部国家重点研发计划（2019YFC1605201）；黑龙江省卫生健康委科研课题（2020 – 195）

详细信息

作者简介:
高飞（1980 – ），男，黑龙江哈尔滨人，主任技师，硕士，主要从事食品安全风险监测和食品安全事故现场调查处置等工作

通信作者:
刘忠卫，E-mail：1127754107@qq.com

中图分类号: R 57
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- 被引次数: 0
出版历程
- 接收日期: 2022-04-08
- 网络出版日期: 2023-02-24
- 刊出日期: 2023-04-10

Incidence and disease burden of acute gastroenteritis among residents in Heilongjiang province, 2018

1.
Heilongjiang Provincial Center for Disease Control and Prevention, Harbin, Heilongjiang Province 150036, China

摘要

摘要: 目的了解黑龙江省2018年急性胃肠炎的发病情况及其疾病负担，为食源性疾病防控策略的制订提供循证依据。方法收集2018年1 — 12月黑龙江省社区人群调查、哨点医院食源性疾病监测数据和相关文献数据构建疾病负担金字塔模型估计黑龙江省急性胃肠炎的病例数，并采用伤残调整生命年（DALYs）对急性胃肠炎导致的疾病健康负担进行分析。结果黑龙江省2018年急性胃肠炎估计病例数共计133814（95%CI = 105635～169334）例，月患病率为3.54%（95%CI = 3.28%～3.80%），发病率为0.47次/人年；黑龙江省因急性胃肠炎所导致的DALYs共计11320.40（95%CI = 9239.09～13947.73）人年，即0.30（95%CI = 0.25～0.37）人年/千人，其中以＜5岁和 ≥ 60岁年龄组人群急性胃肠炎疾病负担最重，分别为0.53（95%CI = 0.21～0.42）人年/千人和0.68（95%CI = 0.49～0.96）人年/千人。结论黑龙江省急性胃肠炎的发病率较高，< 5岁和 ≥ 60岁人群是急性胃肠炎发病的重点人群，应对其重点监测与防控。
- 急性胃肠炎 /
- 发病情况 /
- 疾病负担 /
- 金字塔模型
Abstract: Objective To estimate the incidence and burden of acute gastroenteritis among residents in Heilongjiang province, and to provide evidence for developing strategies on food-borne disease prevention and control. Methods The data on residents′ acute gastroenteritis incidence during 2018 were collected from community population surveys and hospital-based foodborne disease surveillance in Heilongjiang province and a pyramid model of disease burden was constructed to estimate total number of acute gastroenteritis cases in the province. The health burden of acute gastroenteritis was measured with disability adjusted life years (DALYs). Results For whole population of the province in 2018, the estimated number of acute gastroenteritis cases was 133 814 (95% confidence interval [95%CI]: 105 635 – 169 334); the monthly prevalence was 3.54% (95%CI: 3.28% – 3.80%); and the incidence was 0.470/person year. The DALYs due to acute gastroenteritis was 11 320.40 (95%CI: 9239.09 – 13947.73) and the DALYs rate of the disease was 0.30 (95%CI: 0.25 – 0.37)/1 000 population, with the highest DALYs rate for the residents aged < 5 years (0.526 [95%CI: 0.24 – 1.41]/1 000 population) and the residents aged ≥ 60 years (0.680 [95%CI: 0.49 – 0.96]/1 000 population), respectively. Conclusion The incidence of acute gastroenteritis was high among residents of Heilongjiang province, especially among the children under 5 years and the elderly over 60 years.
- acute gastroenteritis /
- incidence /
- disease burden /
- pyramid model

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图 1 急性胃肠炎金字塔模型

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表 1 急性胃肠炎病例数估计相关参数及数据来源

比例	输入分布	数据来源
P₄敏感度	Triang(0.80，0.875，1)	文献[10-13]
P₃检测率	Beta(检测人数 + 1，采样人数 – 检测人数 + 1)	哨点医院监测
P₂采样率	Beta(采样人数 + 1，就诊人数 – 采样人数 + 1)	哨点医院监测
P₁就诊率	Beta(就诊人数 + 1，发病人数 – 就诊人数 + 1)	人群调查调查

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表 2 黑龙江省2018年不同年龄组急性胃肠炎疾病负担情况

年龄（岁）	就诊组		未就诊组		合计
年龄（岁）	DALYs（人年）	95%CI	DALYs（人年）	95%CI	DALYs（人年）	95%CI
< 5	223.82	213.01～234.95	412.84	63.31～1491.08	636.66	288.11～1714.66
5～14	201.48	190.42～212.79	944.88	128.37～4036.60	1146.36	329.11～4246.14
15～44	247.00	234.43～259.85	1022.11	591.08～1714.35	1269.10	840.21～1960.33
45～59	605.51	585.70～625.55	2370.06	1519.29～3664.53	2975.57	2123.42～4268.92
≥ 60	1061.41	1035.36～1087.82	4029.14	2629.68～6113.15	5090.55	3691.98～7169.88
合计	2338.68	2299.72～2377.94	8981.72	6895.15～11612.36	11320.40	9239.09～13947.73

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