Incidence and disease burden of acute gastroenteritis among residents in Heilongjiang province, 2018
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摘要:
目的 了解黑龙江省2018年急性胃肠炎的发病情况及其疾病负担,为食源性疾病防控策略的制订提供循证依据。 方法 收集2018年1 — 12月黑龙江省社区人群调查、哨点医院食源性疾病监测数据和相关文献数据构建疾病负担金字塔模型估计黑龙江省急性胃肠炎的病例数,并采用伤残调整生命年(DALYs)对急性胃肠炎导致的疾病健康负担进行分析。 结果 黑龙江省2018年急性胃肠炎估计病例数共计133814(95%CI = 105635~169334)例,月患病率为3.54%(95%CI = 3.28%~3.80%),发病率为0.47次/人年;黑龙江省因急性胃肠炎所导致的DALYs共计11320.40(95%CI = 9239.09~13947.73)人年,即0.30(95%CI = 0.25~0.37)人年/千人,其中以<5岁和 ≥ 60岁年龄组人群急性胃肠炎疾病负担最重,分别为0.53(95%CI = 0.21~0.42)人年/千人和0.68(95%CI = 0.49~0.96)人年/千人。 结论 黑龙江省急性胃肠炎的发病率较高,< 5岁和 ≥ 60岁人群是急性胃肠炎发病的重点人群,应对其重点监测与防控。 Abstract:Objective To estimate the incidence and burden of acute gastroenteritis among residents in Heilongjiang province, and to provide evidence for developing strategies on food-borne disease prevention and control. Methods The data on residents′ acute gastroenteritis incidence during 2018 were collected from community population surveys and hospital-based foodborne disease surveillance in Heilongjiang province and a pyramid model of disease burden was constructed to estimate total number of acute gastroenteritis cases in the province. The health burden of acute gastroenteritis was measured with disability adjusted life years (DALYs). Results For whole population of the province in 2018, the estimated number of acute gastroenteritis cases was 133 814 (95% confidence interval [95%CI]: 105 635 – 169 334); the monthly prevalence was 3.54% (95%CI: 3.28% – 3.80%); and the incidence was 0.470/person year. The DALYs due to acute gastroenteritis was 11 320.40 (95%CI: 9239.09 – 13947.73) and the DALYs rate of the disease was 0.30 (95%CI: 0.25 – 0.37)/1 000 population, with the highest DALYs rate for the residents aged < 5 years (0.526 [95%CI: 0.24 – 1.41]/1 000 population) and the residents aged ≥ 60 years (0.680 [95%CI: 0.49 – 0.96]/1 000 population), respectively. Conclusion The incidence of acute gastroenteritis was high among residents of Heilongjiang province, especially among the children under 5 years and the elderly over 60 years. -
Key words:
- acute gastroenteritis /
- incidence /
- disease burden /
- pyramid model
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表 1 急性胃肠炎病例数估计相关参数及数据来源
表 2 黑龙江省2018年不同年龄组急性胃肠炎疾病负担情况
年龄(岁) 就诊组 未就诊组 合计 DALYs(人年) 95%CI DALYs(人年) 95%CI DALYs(人年) 95%CI < 5 223.82 213.01~234.95 412.84 63.31~1491.08 636.66 288.11~1714.66 5~14 201.48 190.42~212.79 944.88 128.37~4036.60 1146.36 329.11~4246.14 15~44 247.00 234.43~259.85 1022.11 591.08~1714.35 1269.10 840.21~1960.33 45~59 605.51 585.70~625.55 2370.06 1519.29~3664.53 2975.57 2123.42~4268.92 ≥ 60 1061.41 1035.36~1087.82 4029.14 2629.68~6113.15 5090.55 3691.98~7169.88 合计 2338.68 2299.72~2377.94 8981.72 6895.15~11612.36 11320.40 9239.09~13947.73 -
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