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广东省2021年诺如病毒感染疫情流行病学特征分析

李彩霞 梁玉凤 徐静 张昌 曾汉日 龙勇 柯碧霞

李彩霞, 梁玉凤, 徐静, 张昌, 曾汉日, 龙勇, 柯碧霞. 广东省2021年诺如病毒感染疫情流行病学特征分析[J]. 中国公共卫生, 2022, 38(11): 1369-1372. doi: 10.11847/zgggws1138942
引用本文: 李彩霞, 梁玉凤, 徐静, 张昌, 曾汉日, 龙勇, 柯碧霞. 广东省2021年诺如病毒感染疫情流行病学特征分析[J]. 中国公共卫生, 2022, 38(11): 1369-1372. doi: 10.11847/zgggws1138942
LI Cai-xia, LIANG Yu-feng, XU Jing, . Prevalence and genetic characteristics of norovirus epidemics in Guangdong province, 2021[J]. Chinese Journal of Public Health, 2022, 38(11): 1369-1372. doi: 10.11847/zgggws1138942
Citation: LI Cai-xia, LIANG Yu-feng, XU Jing, . Prevalence and genetic characteristics of norovirus epidemics in Guangdong province, 2021[J]. Chinese Journal of Public Health, 2022, 38(11): 1369-1372. doi: 10.11847/zgggws1138942

广东省2021年诺如病毒感染疫情流行病学特征分析

doi: 10.11847/zgggws1138942
基金项目: 广东省省级科技计划项目(2019B030316013)
详细信息
    作者简介:

    李彩霞(1982 – ),女,广东广州人,博士,研究方向:诺如病毒及肠道病毒的致病机制

    通讯作者:

    柯碧霞,E-mail:2212935520@qq.com

  • 中图分类号: R 511

Prevalence and genetic characteristics of norovirus epidemics in Guangdong province, 2021

  • 摘要:   目的  分析2021年广东省诺如病毒聚集性或暴发疫情的流行病学特征。  方法  收集广东省2021年1 — 12月诺如病毒感染疫情样本及相关基本信息,通过实时荧光定量PCR(qRT-PCR)对样本进行诺如病毒的鉴定,筛选诺如病毒GI型和GII型阳性样本,通过PCR扩增、建库、测序、序列拼接后对其进行基因分型。  结果  2021年广东省共报告141起诺如病毒感染疫情,其中92.91 %(131起)的疫情发生在托幼机构或学校;疫情的流行季节为冬春季。73起疫情(51.77 %)确定了基因分型。94.52 %(133起)的诺如病毒感染疫情由GII型引起,其中GII.2[P16]和GII.4[P31]分别占比39.13 % 和23.19 %。  结论  广东省2021年诺如病毒疫情主要发生在托幼机构和学校,GII.2[P16]和GII.4[P31]分别是春季和冬季的主要流行型别,仍需继续加强诺如病毒疫情监测以及分子分型研究。
  • 图  1  2021年广东省不同月份NV疫情相关基因型分布

    表  1  2021年广东省NV疫情发生场所与NV基因型分布

    基因型疫情发生场所(起)合计
    托幼机构中小学职业技术学院大学集体单位社区及家庭酒店
    GII.2[P16]10150020027
    GII.3[P12]12100004
    GII.4[P16]20001003
    GII.17[P17]271010112
    GII.8[P8]11000002
    GII.6[P7]13010005
    GII.4[P31]1410100016
    GI.6[P11]01100002
    GI.4[P4]01000001
    混合基因型00010001
    未知基因型30282332068
    合计615956721141
    下载: 导出CSV
  • [1] Fumian TM, Fioretti JM, Lun JH, et al. Detection of norovirus epidemic genotypes in raw sewage using next generation sequenc-ing[J]. Environment International, 2019, 123: 282 – 291. doi: 10.1016/j.envint.2018.11.054
    [2] Jin M, Wu SY, Kong XY, et al. Norovirus outbreak surveillance, China, 2016 – 2018[J]. Emerging Infectious Diseases, 2020, 26(3): 437 – 445. doi: 10.3201/eid2603.191183
    [3] Robilotti E, Deresinski S, Pinsky BA. Norovirus[J]. Clinical Microbiology Reviews, 2015, 28(1): 134 – 164. doi: 10.1128/CMR.00075-14
    [4] Chhabra P, de Graaf M, Parra GI, et al. Updated classification of norovirus genogroups and genotypes[J]. Journal of General Virology, 2019, 100(10): 1393 – 1406. doi: 10.1099/jgv.0.001318
    [5] Ao YY, Wang JJ, Ling H, et al. Norovirus GII. P16/GII. 2-associated gastroenteritis, China, 2016[J]. Emerging Infectious Diseases, 2017, 23(7): 1172 – 1175. doi: 10.3201/eid2307.170034
    [6] 廖巧红, 冉陆, 靳森, 等. 诺如病毒感染暴发调查和预防控制技术指南(2015版)[J]. 中华预防医学杂志, 2016, 50(1): 7 – 16. doi: 10.3760/cma.j.issn.0253-9624.2016.01.003
    [7] 张萌, 龙遗芳, 郭莉敏, 等. 广东省2013 — 2017年3种基因型诺如病毒感染暴发疫情的流行特征[J]. 中华流行病学杂志, 2018, 39(9): 1210 – 1215. doi: 10.3760/cma.j.issn.0254-6450.2018.09.013
    [8] 苏文哲, 耿进妹, 赖赛麟, 等. 诺如病毒重组株GII. P16 – GII. 2在广州地区引起暴发的分子流行病学调查[J]. 中华实验和临床病毒学杂志, 2019, 33(4): 362 – 368. doi: 10.3760/cma.j.issn.1003-9279.2019.04.006
    [9] Grant LR, O′Brien KL, Weatherholtz RC, et al. Norovirus and sapovirus epidemiology and strain characteristics among Navajo and Apache infants[J]. PLoS One, 2017, 12(1): e0169491. doi: 10.1371/journal.pone.0169491
    [10] Bruggink LD, Garcia-Clapes A, Tran T, et al. Decreased incidence of enterovirus and norovirus infections during the COVID-19 pandemic, Victoria, Australia, 2020[J]. Communicable Diseases Intelligence (2018), 2021: 45. doi: 10.33321/cdi.2021.45.5.
    [11] Nachamkin I, Richard-Greenblatt M, Yu M, et al. Reduction in sporadic norovirus infections following the start of the COVID-19 pandemic, 2019 – 2020, Philadelphia[J]. Infectious Diseases and Therapy, 2021, 10(3): 1793 – 1798. doi: 10.1007/s40121-021-00473-z
    [12] O′Reilly KM, Sandman F, Allen D, et al. Predicted norovirus resur-gence in 2021 – 2022 due to the relaxation of nonpharmaceutical interventions associated with COVID-19 restrictions in England: a mathematical modeling study[J]. BMC Medicine, 2021, 19(1): 299. doi: 10.1186/s12916-021-02153-8
    [13] Steele MK, Wikswo ME, Hall AJ, et al. Characterizing norovirus transmission from outbreak data, United States[J]. Emerging Infectious Diseases, 2020, 26(8): 1818 – 1825. doi: 10.3201/eid2608.191537
    [14] Hasing ME, Lee BE, Qiu YY, et al. Changes in norovirus genotype diversity in gastroenteritis outbreaks in Alberta, Canada: 2012 – 2018[J]. BMC Infectious Diseases, 2019, 19(1): 177. doi: 10.1186/s12879-019-3792-y
    [15] Wei N, Ge J, Tan CY, et al. Epidemiology and evolution of Norovirus in China[J]. Human Vaccines and Immunotherapeutics, 2021, 17(11): 4553 – 4566. doi: 10.1080/21645515.2021.1961465
    [16] Fang XY, Ai J, Liu WD, et al. Epidemiology of infectious diarrhoea and the relationship with etiological and meteorological factors in Jiangsu province, China[J]. Scientific Reports, 2019, 9(1): 19571. doi: 10.1038/s41598-019-56207-2
    [17] Liu LTC, Kuo TY, Wu CY, et al. Recombinant GII. P16-GII.2 norovirus, Taiwan, 2016[J]. Emerging Infectious Diseases, 2017, 23(7): 1180 – 1183. doi: 10.3201/eid2307.170212
    [18] Geng Q, Shen Y, Shi P, et al. Epidemiologic features and influencing factors of norovirus outbreaks in the city of Wuxi, China from 2014 to 2018[J]. The American Journal of Tropical Medicine and Hygiene, 2021, 105(6): 1575 – 1581. doi: 10.4269/ajtmh.20-1371
    [19] Han JK, Ji L, Shen YH, et al. Emergence and predominance of norovirus GII. 17 in Huzhou, China, 2014 – 2015[J]. Virology Journal, 2015, 12: 139. doi: 10.1186/s12985-015-0370-9
    [20] Wang J, Jin M, Zhang HL, et al. Norovirus GII.2[P16] strain in Shenzhen, China: a retrospective study[J]. BMC Infectious Diseases, 2021, 21(1): 1122. doi: 10.1186/s12879-021-06746-9
    [21] Zhu X, He YQ, Wei XY, et al. Molecular epidemiological characteristics of gastroenteritis outbreaks caused by norovirus GII.4 sydney [P31] strains – China, October 2016 – December 2020[J]. China CDC Weekly, 2021, 3(53): 1127 – 1132. doi: 10.46234/ccdcw2021.276
    [22] Wang H, Wang DH, Chen C, et al. Epidemiologic characteristics of outbreaks of three norovirus genotypes (GII.2, GII.17 and GII.4 Sydney) in Guangzhou, China, from 2012 to 2018[J]. Epidemiology and Infection, 2019, 147: e207. doi: 10.1017/S0950268819000992
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出版历程
  • 收稿日期:  2022-04-25
  • 网络出版日期:  2022-11-24
  • 刊出日期:  2022-11-30

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