微塑料对人体健康潜在影响研究进展

潘燕彬; 颜建龙; 董少红; 吴伟晴; 罗伟香; 彭粤铭; 林小兰; 黄琼芳

doi:10.11847/zgggws1140359

微塑料对人体健康潜在影响研究进展

doi: 10.11847/zgggws1140359

1.
深圳市人民医院（暨南大学第二临床医学院南方科技大学第一附属医院）健康管理科，广东 518020
2.
深圳市人民医院（暨南大学第二临床医学院南方科技大学第一附属医院）心血管内科深圳市心血管微创医学工程技术研究开发中心
3.
深圳市人民医院（暨南大学第二临床医学院南方科技大学第一附属医院）护理部

详细信息

作者简介:
潘燕彬（1992 – ），女，广东佛山人，硕士，主要从事健康管理工作

通讯作者:
颜建龙，E-mail：935428653@qq.com

中图分类号: X 505；X 503.1
计量
- 文章访问数: 53
- HTML全文浏览量: 11
- PDF下载量: 20
- 被引次数: 0
出版历程
- 接收日期: 2022-09-17
- 网络出版日期: 2023-03-31
- 刊出日期: 2023-04-10

Potential impact of microplastics on human health: research progress

1.
Department of Health Management, Shenzhen People’s Hospital, Shenzhen, Guangdong Province 518020, China

摘要

摘要: 微塑料污染是一个日益严重的生态问题，不可避免地通过饮食摄入、空气吸入和皮肤接触的方式暴露于人体。本文概述了微塑料的特性、微塑料在人体中的暴露途径和微塑料对各系统产生的潜在影响，以期为后续微塑料在人体健康方面的研究提供参考。
- 微塑料 /
- 健康状况 /
- 影响 /
- 人体
Abstract: Microplastic pollution is a growing ecological problem and human exposure to micrioplastic through dietary intake, air inhalation and skin-to-skin contact is inevitable. This study provides an overview on the properties of microplastics, the pathways of microplastic exposure in humans, and potential impact of microplastics on human body systems as a reference to future research.
- microplastics /
- health status /
- impact /
- human body

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参考文献(61)

[1]	Barboza LGA, Dick Vethaak A, Lavorante BRBO, et al. Marine microplastic debris: an emerging issue for food security, food safety and human health[J]. Marine Pollution Bulletin, 2018, 133: 336 – 348. doi: 10.1016/j.marpolbul.2018.05.047
[2]	Zarus GM, Muianga C, Hunter CM, et al. A review of data for quantifying human exposures to micro and nanoplastics and potential health risks[J]. Science of the Total Environment, 2021, 756: 144010. doi: 10.1016/j.scitotenv.2020.144010
[3]	Thompson RC, Swan SH, Moore CJ, et al. Our plastic age[J]. Philosophical Transactions of the Royal Society B:Biological Sciences, 2009, 364(1526): 1973 – 1976. doi: 10.1098/rstb.2009.0054
[4]	Rhodes CJ. Plastic pollution and potential solutions[J]. Science Progress, 2018, 101(3): 207 – 260’. doi: 10.3184/003685018X15294876706211
[5]	Münzel T, Hahad O, Daiber A, et al. Soil and water pollution and human health: what should cardiologists worry about?[J]. Cardio-vascular Research, 2022,doi: 10.1093/cvr/cvac082.
[6]	Walkinshaw C, Lindeque PK, Thompson R, et al. Microplastics and seafood: lower trophic organisms at highest risk of conta-mination[J]. Ecotoxicology and Environmental Safety, 2020, 190: 110066. doi: 10.1016/j.ecoenv.2019.110066
[7]	Thompson RC, Olsen Y, Mitchell RP, et al. Lost at sea: where is all the plastic?[J]. Science, 2004, 304(5672): 838. doi: 10.1126/science.1094559
[8]	Yang X, Man YB, Wong MH, et al. Environmental health impacts of microplastics exposure on structural organization levels in the human body[J]. Science of the Total Environment, 2022, 825: 154025. doi: 10.1016/j.scitotenv.2022.154025
[9]	Hartmann NB, Hüffer T, Thompson RC, et al. Are we speaking the same language? Recommendations for a definition and categoriza-tion framework for plastic debris[J]. Environmental Science and Technology, 2019, 53(3): 1039 – 1047. doi: 10.1021/acs.est.8b05297
[10]	Sun Q, Ren SY, Ni HG. Incidence of microplastics in personal care products: an appreciable part of plastic pollution[J]. Science of the Total Environment, 2020, 742: 140218. doi: 10.1016/j.scitotenv.2020.140218
[11]	Wang WF, Ge J, Yu XY. Bioavailability and toxicity of microplastics to fish species: a review[J]. Ecotoxicology and Environmental Safety, 2020, 189: 109913. doi: 10.1016/j.ecoenv.2019.109913
[12]	Zhu JM, Zhang Q, Li YP, et al. Microplastic pollution in the Maowei Sea, a typical mariculture bay of China[J]. Science of the Total Environment, 2019, 658: 62 – 68. doi: 10.1016/j.scitotenv.2018.12.192
[13]	Van Cauwenberghe L, Janssen CR. Microplastics in bivalves cultured for human consumption[J]. Environmental Pollution, 2014, 193: 65 – 70. doi: 10.1016/j.envpol.2014.06.010
[14]	Li JN, Green C, Reynolds A, et al. Microplastics in mussels sampled from coastal waters and supermarkets in the United Kingdom[J]. Environmental Pollution, 2018, 241: 35 – 44. doi: 10.1016/j.envpol.2018.05.038
[15]	Pfaller JB, Goforth KM, Gil MA, et al. Odors from marine plastic debris elicit foraging behavior in sea turtles[J]. Current Biology, 2020, 30(5): R213 – R214. doi: 10.1016/j.cub.2020.01.071
[16]	Cheng Z, Nie XP, Wang HS, et al. Risk assessments of human exposure to bioaccessible phthalate esters through market fish consumption[J]. Environment International, 2013, 57 – 58: 75 – 80.
[17]	Chan HSH, Dingle C, Not C. Evidence for non-selective ingestion of microplastic in demersal fish[J]. Marine Pollution Bulletin, 2019, 149: 110523. doi: 10.1016/j.marpolbul.2019.110523
[18]	华正罡, 李良, 那军, 等. 污泥堆放场地附近饲养生猪肠组织微塑料污染状况调查[J]. 中国公共卫生, 2021, 37(3): 455 – 460. doi: 10.11847/zgggws1134513-new
[19]	Dou PC, Mai L, Bao LJ, et al. Microplastics on beaches and mangrove sediments along the coast of South China[J]. Marine Pollution Bulletin, 2021: 172.
[20]	Ebere EC, Wirnkor VA, Ngozi VE. Uptake of microplastics by plant: a reason to worry or to be happy?[J]. World Scientific News, 2019, 131: 256 – 267.
[21]	Conti GO, Ferrante M, Banni M, et al. Micro- and nano-plastics in edible fruit and vegetables. The first diet risks assessment for the general population[J]. Environmental Research, 2020, 187: 109677. doi: 10.1016/j.envres.2020.109677
[22]	Schymanski D, Goldbeck C, Humpf HU, et al. Analysis of microplastics in water by micro-Raman spectroscopy: release of plastic particles from different packaging into mineral water[J]. Water Research, 2018, 129: 154 – 162. doi: 10.1016/j.watres.2017.11.011
[23]	Zuccarello P, Ferrante M, Cristaldi A, et al. Exposure to microplastics (< 10 μm) associated to plastic bottles mineral water consumption: the first quantitative study[J]. Water Research, 2019, 157: 365 – 371. doi: 10.1016/j.watres.2019.03.091
[24]	Winkler A, Santo N, Ortenzi MA, et al. Does mechanical stress cause microplastic release from plastic water bottles?[J]. Water Research, 2019, 166: 115082. doi: 10.1016/j.watres.2019.115082
[25]	Chen GL, Feng QY, Wang J. Mini-review of microplastics in the atmosphere and their risks to humans[J]. Science of the Total Environment, 2020, 703: 135504. doi: 10.1016/j.scitotenv.2019.135504
[26]	Liu K, Wang XH, Fang T, et al. Source and potential risk assessment of suspended atmospheric microplastics in Shanghai[J]. Science of the Total Environment, 2019, 675: 462 – 471. doi: 10.1016/j.scitotenv.2019.04.110
[27]	Henry B, Laitala K, Klepp IG. Microfibres from apparel and home textiles: prospects for including microplastics in environmental sustainability assessment[J]. Science of the Total Environment, 2019, 652: 483 – 494. doi: 10.1016/j.scitotenv.2018.10.166
[28]	Enyoh CE, Verla AW, Verla EN, et al. Airborne microplastics: a review study on method for analysis, occurrence, movement and risks[J]. Environmental Monitoring and Assessment, 2019, 191(11): 668. doi: 10.1007/s10661-019-7842-0
[29]	Prata JC. Airborne microplastics: consequences to human health?[J]. Environmental Pollution, 2018, 234: 115 – 126. doi: 10.1016/j.envpol.2017.11.043
[30]	Abbasi S, Keshavarzi B, Moore F, et al. Distribution and potential health impacts of microplastics and microrubbers in air and street dusts from Asaluyeh County, Iran[J]. Environmental Pollution, 2019, 244: 153 – 164. doi: 10.1016/j.envpol.2018.10.039
[31]	Vianello A, Jensen RL, Liu L, et al. Simulating human exposure to indoor airborne microplastics using a Breathing Thermal Manikin[J]. Scientific Reports, 2019, 9(1): 8670. doi: 10.1038/s41598-019-45054-w
[32]	那军, 耿译航, 蒋莹, 等. 快递员痰液和鼻腔冲洗液中微塑料污染分析[J]. 中国公共卫生, 2021, 37(3): 451 – 454. doi: 10.11847/zgggws1134512
[33]	Kole PJ, Löhr AJ, Van Belleghem FGAJ, et al. Wear and tear of tyres: a stealthy source of microplastics in the environment[J]. International Journal of Environmental Research and Public Health, 2017, 14(10): 1265. doi: 10.3390/ijerph14101265
[34]	Schneider M, Stracke F, Hansen S, et al. Nanoparticles and their interactions with the dermal barrier[J]. Dermato-Endocrinology, 2009, 1(4): 197 – 206. doi: 10.4161/derm.1.4.9501
[35]	Anagnosti L, Varvaresou A, Pavlou P, et al. Worldwide actions against plastic pollution from microbeads and microplastics in cosmetics focusing on European policies. Has the issue been handled effectively?[J]. Marine Pollution Bulletin, 2021, 162: 111883. doi: 10.1016/j.marpolbul.2020.111883
[36]	Kuo TR, Wu CL, Hsu CT, et al. Chemical enhancer induced changes in the mechanisms of transdermal delivery of zinc oxide nanoparticles[J]. Biomaterials, 2009, 30(16): 3002 – 3008. doi: 10.1016/j.biomaterials.2009.02.003
[37]	Yurtsever M. Tiny, shiny, and colorful microplastics: are regular glitters a significant source of microplastics?[J]. Marine Pollution Bulletin, 2019, 146: 678 – 682. doi: 10.1016/j.marpolbul.2019.07.009
[38]	Lelieveld J, Klingmüller K, Pozzer A, et al. Cardiovascular disease burden from ambient air pollution in Europe reassessed using novel hazard ratio functions[J]. European Heart Journal, 2019, 40(20): 1590 – 1596. doi: 10.1093/eurheartj/ehz135
[39]	Landrigan PJ, Fuller R, Acosta NJR, et al. The Lancet Commission on pollution and health[J]. The Lancet, 2018, 391(10119): 462 – 512. doi: 10.1016/S0140-6736(17)32345-0
[40]	Dong CD, Chen CW, Chen YC, et al. Polystyrene microplastic particles: in vitro pulmonary toxicity assessment[J]. Journal of Hazardous Materials, 2020, 385: 121575. doi: 10.1016/j.jhazmat.2019.121575
[41]	Geiser M, Stoeger T, Casaulta M, et al. Biokinetics of nanoparticles and susceptibility to particulate exposure in a murine model of cystic fibrosis[J]. Particle and Fibre Toxicology, 2014, 11: 19. doi: 10.1186/1743-8977-11-19
[42]	Lim D, Jeong J, Song KS, et al. Inhalation toxicity of polystyrene micro (nano) plastics using modified OECD TG 412[J]. Chemo-sphere, 2021, 262: 128330. doi: 10.1016/j.chemosphere.2020.128330
[43]	Bouwmeester H, Hollman PCH, Peters RJB. Potential health impact of environmentally released micro- and nanoplastics in the human food production chain: experiences from nanotoxic-ology[J]. Environmental Science and Technology, 2015, 49(15): 8932 – 8947. doi: 10.1021/acs.est.5b01090
[44]	Carbery M, O′Connor W, Palanisami T. Trophic transfer of microplastics and mixed contaminants in the marine food web and implications for human health[J]. Environment International, 2018, 115: 400 – 409. doi: 10.1016/j.envint.2018.03.007
[45]	Schwabl P, Köppel S, Königshofer P, et al. Detection of various microplastics in human stool: a prospective case series[J]. Annals of Internal Medicine, 2019, 171(7): 453 – 457. doi: 10.7326/M19-0618
[46]	Ibrahim YS, Tuan Anuar S, Azmi AA, et al. Detection of microplastics in human colectomy specimens[J]. JGH Open, 2021, 5(1): 116 – 12157. doi: 10.1002/jgh3.12457
[47]	Mahler GJ, Esch MB, Tako E, et al. Oral exposure to polystyrene nanoparticles affects iron absorption[J]. Nature Nanotechnology, 2012, 7(4): 264 – 271. doi: 10.1038/nnano.2012.3
[48]	谢琼, 于慧慧, 周长赫, 等. 微纳米塑料在小鼠消化器官吸收分布及与脂肪亲和性[J]. 中国公共卫生, 2021, 37(3): 446 – 450. doi: 10.11847/zgggws1134472
[49]	Liu ZQ, Yu P, Cai MQ, et al. Effects of microplastics on the innate immunity and intestinal microflora of juvenile Eriocheir sinensis[J]. Science of the Total Environment, 2019, 685: 836 – 846. doi: 10.1016/j.scitotenv.2019.06.265
[50]	Jin YX, Xia JZ, Pan ZH, et al. Polystyrene microplastics induce microbiota dysbiosis and inflammation in the gut of adult zebrafish[J]. Environmental Pollution, 2018, 235: 322 – 329. doi: 10.1016/j.envpol.2017.12.088
[51]	Ragusa A, Svelato A, Santacroce C, et al. Plasticenta: first evidence of microplastics in human placenta[J]. Environment International, 2021, 146: 106274. doi: 10.1016/j.envint.2020.106274
[52]	Tallec K, Huvet A, Di Poi C, et al. Nanoplastics impaired oyster free living stages, gametes and embryos[J]. Environmental Pollution, 2018, 242: 1226 – 1235. doi: 10.1016/j.envpol.2018.08.020
[53]	Cole M, Lindeque P, Fileman E, et al. The impact of polystyrene microplastics on feeding, function and fecundity in the marine copepod Calanus helgolandicus[J]. Environmental Science and Technology, 2015, 49(2): 1130 – 1137. doi: 10.1021/es504525u
[54]	Luo T, Wang CY, Pan ZH, et al. Maternal polystyrene microplastic exposure during gestation and lactation altered metabolic homeo-stasis in the dams and their F1 and F2 offspring[J]. Environmental Science and Technology, 2019, 53(18): 10978 – 10992. doi: 10.1021/acs.est.9b03191
[55]	王洪艳, 李环, 张晶. 聚乙烯、聚丙烯微塑料致雄性小鼠生殖毒性的联合效应[J]. 北华大学学报(自然科学版), 2022, 23(4): 478 – 482.
[56]	Bhatnagar A. Environmental determinants of cardiovascular disease[J]. Circulation Research, 2017, 121(2): 162 – 180. doi: 10.1161/CIRCRESAHA.117.306458
[57]	Brook RD, Rajagopalan S, Pope III CA, et al. Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association[J]. Circulation, 2010, 121(21): 2331 – 2378. doi: 10.1161/CIR.0b013e3181dbece1
[58]	Münzel T, Sørensen M, Gori T, et al. Environmental stressors and cardio-metabolic disease: part II – mechanistic insights[J]. European Heart Journal, 2017, 38(8): 557 – 564.
[59]	Zhao JJ, Gomes D, Jin LX, et al. Polystyrene bead ingestion promotes adiposity and cardiometabolic disease in mice[J]. Ecotoxicology and Environmental Safety, 2022, 232: 113239. doi: 10.1016/j.ecoenv.2022.113239
[60]	Wei JL, Wang XF, Liu Q, et al. The impact of polystyrene microplastics on cardiomyocytes pyroptosis through NLRP3/Caspase-1 signaling pathway and oxidative stress in Wistar rats[J]. Environmental Toxicology, 2021, 36(5): 935 – 944. doi: 10.1002/tox.23095
[61]	Cammalleri V, Marotta D, Antonucci A, et al. A survey on knowledge and awareness on the issue “microplastics”: a pilot study on a sample of future public health professionals[J]. Annali Di Igiene, 2020, 32(5): 577 – 589.