Abstract: The aim of the study was to explore the risk factors of pulmonary adenocarcinoma among female in Shenyang of China.A casecontrol study based on general population was designed and multivariable logistic regression model was applied.72 pulmonary adenocacinoma cases of new diagnosis duration from January,1991 to December,1995,ages 35～69,were studied by 1:1 match.The results showed that the cooking fumes,family history of lung cancer,economic income,numbers of live births and vitamin E were significant risk factors assoiated with adenocarcinoma of the lung.The βcarotene of intak from vegetables and fruits was a protective factor and protective level was 028(95% CI,0.12～0.69),Analysis of the relationship between the indoor air pollution and adenocarcinoma of the lung showed that the risk increased with the level of exposure to cooking fumes increased.The odds ratioin the different levels were 1.33,7.33,1.67 respectively and indicated the doserespond relationship(tend p=0.006).The other important factor was the family history of lung cancer,the OR was 7.65 folds(95% CI,0.90～169.84).The result of multivariable logisic regression model for pulmonary adenocarcinoma among female showed the same results after adjusting confounding factors.