Abstract: The effect of deratization and the drop if rat density were evaluated with the methods of one time baiting in major habitats within the scope of deratization on baiting in minor habitats,only a survey made on rat density before and after deratization,determination of rat density with the night trapping method.The results showed that the effects of deratization with Brodifacoum,Bromadiolone and Zinc phosphide were 100%,100% and 96.83% respectively to the major habitas.The rat density dropped by 87.95% and 97.24% respectively in minor and whole habitats after baiting only in major habitats.This method could save 70% rodenticide and 80% labour,compared with the traditional universal baiting method.We believe that this method,which is reliable,convenient and economical,can effectively control the rat density in hilly areas,and is of great significance in the effective control of epidemics of Epidemic Hemorrhagic Fever(EHF) and of great academic value and value of spread and application.