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孙英杰, 马艳, 刘春梅, 田疆, 顾松义, 林桂芹. 1999年辽宁省健康人群抗麻疹病毒中和抗体测定结果与麻疹发病率关系的分析[J]. 中国公共卫生, 2001, 17(3): 203-204. DOI: 10.11847/zgggws2001-17-03-07
引用本文: 孙英杰, 马艳, 刘春梅, 田疆, 顾松义, 林桂芹. 1999年辽宁省健康人群抗麻疹病毒中和抗体测定结果与麻疹发病率关系的分析[J]. 中国公共卫生, 2001, 17(3): 203-204. DOI: 10.11847/zgggws2001-17-03-07
SUN Ying-jie, . Result Analysis of Neutralization Antibody against Measles Virus of the Health People was Detected with Measles Virus Incidence in the Liaoning Province in 1999[J]. Chinese Journal of Public Health, 2001, 17(3): 203-204. DOI: 10.11847/zgggws2001-17-03-07
Citation: SUN Ying-jie, . Result Analysis of Neutralization Antibody against Measles Virus of the Health People was Detected with Measles Virus Incidence in the Liaoning Province in 1999[J]. Chinese Journal of Public Health, 2001, 17(3): 203-204. DOI: 10.11847/zgggws2001-17-03-07

1999年辽宁省健康人群抗麻疹病毒中和抗体测定结果与麻疹发病率关系的分析

Result Analysis of Neutralization Antibody against Measles Virus of the Health People was Detected with Measles Virus Incidence in the Liaoning Province in 1999

  • 摘要: 目的了解辽宁省正常人群不同年龄组抗麻疹病毒抗体免疫水平.方法1999年采集全省6个市地14个区县不同年龄组693份血清,使用B95A细胞以微量细胞培养方法测定抗麻疹病毒中和抗体.结果2~4岁,20~25岁组抗体阳性率为94%,其它年龄组均在96%以上.但是2~4岁GMT开始下降,6~8、9~11岁组最低,这两个年龄组发病率也最高.此结果与1999年麻疹发病率吻合.结论提示儿童在2岁和5岁时应各进行1次麻疹疫苗接种;鉴于1999年13~15岁组麻疹发病率是0.6/10万的情况,建议如果条件允许,14岁以下年龄应每隔5~6年普遍再接种1次麻疹疫苗.

     

    Abstract: ObjectiveTo know neutr alization antibody level ag ainst measles virus(MV)of health people in the Liaoning province.Methods693 serum samples of different age gr oups were collected in 14 counties and districts in 6 areas of the Liaoning pr ovince in 1999.Neutralization antibody was detected by cell micro culture using B95A cell.ResultsThe results indicated that positive rate was 94% in the 2~4 and 20~25 years old groups and in other groups was more than 96%,but GMT was lower in the 2~4 years old group,lowest in 6~8 and 9~11 years old groups.Which conformed to the measles incidence in 1999,the incidence was the highest in the 6~8 and 9~11 years old groups.ConclusionIt points out that children of 2 and 5 years old would be vaccinated by MV vaccine again in order to increase antibody against MV.It is best for children who are unden 14 years old being vaccinated again every 5~6 years if possiblee,because measles incidence was 0.6/100,000 in the 13~15 years old group in 1999 in Liaoning province.

     

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