空气污染对呼吸道微生态的影响
Effects of Air Pollution on Respiratory Tract Microecosystem
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摘要: 目的探讨空气污染对呼吸道菌群的影响,为改善生存环境,预防呼吸道疾患提供科学依据.方法选择重污染区和轻污染区,以没有职业接触,近3个月末用抗生素类药物的6~8岁儿童作为研究对象,对其口咽部菌群进行定性、定量分析,进行对比研究.结果口咽部菌群受外环境的影响较大,重污染区儿童口咽部菌群密度明显高于轻污染区(P<0.01),且需氧菌与厌氧菌之比也明显增高(P<0.01),肺炎链球菌检出率较高,而甲型链球菌检出率较低(P<0.05).结论大气污染对呼吸道菌群的定植具有明显的影响,是使微生态失衡,呼吸道疾病感染率增高的重要因素.Abstract: ObjectiveTo approach the effects of air pollution on respiratory tract flora in order to provide scientific basis for improving existent environment and preventing diseases.MethodsChildren aged 6~8 years from severe and mild pollution areas without occupational exposure and administering antibiotics in the latest three months were selected and determined qualitatively for their oral-pharynx flora.ResultsOral-pharynx flora were greatly affected by external environment.The density of children's oralpharyngeus flora was markedly higher in the severe area than that in the mild one(P<0.01).The ratio of aerobes and anaerobes was obviously increased(P<0.01),and the detecting rate of pneumoocci was higher,However it was lower in α-streptococci (P<0.05).ConclusionAir pollution markedly influenced the field planting of flora in respiratory tract.It was an imponant factor for imbalance of microecosystem and the increasing incidence of reapiratory diseases.