北京地区HFRS病例的主要临床特点和血清学分型

Sero-type and Clinic Characteritics of the Patients with HFRS in Beijing

摘要: 目的搞清北京地区肾综合征出血热病例(HFRS)的血清型别,为确定北京地区疫源地性质提供依据.方法采用微量细胞病变中和试验(MCPENT)对34例HFRS病人的急性期血清进行分型.结果来自12个区(县)不同年度的34例HFRS病人临床表现以轻、中型病例为主,重型病例较少.血清MCPENT分型试验结果33例为汉城型(SEO)HFRS病例,1例ⅠⅡ型中和抗体滴度等同未定型病例.结论SEO型汉坦病毒(HV)为北京地区近年主要流行株,其迅速广泛的蔓延传播为发病显着增多的根本原因.

Abstract: ObjectiveTo understand the sero-type of the patients with HFRS and determine the type of infectious factor in Beijing.MethodsUsing MCPENT to detect the serum of 34 patients with HFRS in acute period and typing them.34 patients live in 12 districts or counties respectively.ResultsMost of the 34 patients have mild or middle clinic symptom 33 of 34 patients are caused by SEO type HV and 1 antibody in serum of typeⅠ and typeⅡ are all 80,so we didn't determine the type of this patient.ConclusionSEO type HV is the main epidemic strain in Beijing.SEO type HV is the infectious factor caused the patients increased.