Abstract: ObjectiveTo study the variety and affect factors of PbB level of pregnant women and babies.MethodsThe PbB level of pregnant women and babies were followed up since the 3^rd month of pregnency until babies were 2 years old.At the same time,the gener al information of delivery,individual,family,husband,infant feeding and development were investigated.The PbB level of pregnant women and infants,variety trend and affecting factors of PbB were determined and analyzed.ResultsThe mean PbB level of pregnant women are respectively 50.3μg/L and 51.6μg/L at 3 and 6 months of gestation,but the mean PbB level rise up to 70.4μg/L near deliver y.The mena PbB level of umbilical coral is 57.4μg/L,which is significantly lower than that near delivery(P<0.05).There is a significant correlation between PbB of umbilical coral and that near delivery(r=0.97,P<0.05).The infant PbB level and percentage of PbB level higher than 100μg/L both increase with aging obviously,the percentage of PbB level of children higher than 100μg/L rise up to 32% in 2-year old children.ConclusionFamily condition can affect PbB level of pregnant women at certain degree.Except the high lead absorptivity of infant,the quick risking of PbB level of infants with age is related with more leadcontacting opportunities of infants.The factors related with infant's lead exposure include house types,infant feeding and the occupation,age and education degree of mother.