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于笑难, 蒋莉, 付炜昕, 高洪福, 富荣威. 血液透析患者病毒性肝炎感染的情况调查[J]. 中国公共卫生, 2002, 18(5): 597-598. DOI: 10.11847/zgggws2002-18-05-51
引用本文: 于笑难, 蒋莉, 付炜昕, 高洪福, 富荣威. 血液透析患者病毒性肝炎感染的情况调查[J]. 中国公共卫生, 2002, 18(5): 597-598. DOI: 10.11847/zgggws2002-18-05-51
YU Xiao-nan, JIANG Li, FU Wei-xin, . Study of Hepatitic Virus Infection in Patients on Hemodialysis[J]. Chinese Journal of Public Health, 2002, 18(5): 597-598. DOI: 10.11847/zgggws2002-18-05-51
Citation: YU Xiao-nan, JIANG Li, FU Wei-xin, . Study of Hepatitic Virus Infection in Patients on Hemodialysis[J]. Chinese Journal of Public Health, 2002, 18(5): 597-598. DOI: 10.11847/zgggws2002-18-05-51

血液透析患者病毒性肝炎感染的情况调查

Study of Hepatitic Virus Infection in Patients on Hemodialysis

  • 摘要: 目的调查血液透析患者乙型、丙型和庚型肝炎病毒感染及其多重感染的情况,探讨其感染的危险因素.方法对1478例血透患者的血清进行HBsAg、HBsAb、HBeAg、HBeAb、HBcAb、HBV-DNA、anti-HCV、anti-HGV的检测.并随机抽取100例anti-HCV和anti-HGV阳性血清RT-PCR方法检测HCV-RNA和HGV-RNA.结果1478例血清中HBV感染率为43.9%,HBV-DNA感染率为7.9%;HCV感染率42.6%;HGV感染率为46.4%.随机抽取100例anti-HCV和anti-HGV阳性血清,HCV-RNA和HGVRNA的感染率分别为73%和77%.HBV合并HCV感染者25.4%,HCV合并HGV感染者21.0%,HCV、HBV、HGV3者合并感染者10.4%.结论血液透析患者存在着经血行感染乙型、丙型和庚型肝炎病毒的高危因素.

     

    Abstract: ObjectiveTo study the infect ion of hepatitis Bvirus(HBV)、hepatitis Cvirus(HCV)and hepatitis G virus on hemodialysis.MethodsHBsAg,HBsAb,HBeAg,HBeAb,HBcAb,and anti-HCV and anti-HGV were measured in 1 478 patients on hemdialysis over 3 mothes by Enzyme Immunassay.HBV-DNA was determined by polymerase chain reaction (PCR).100positive patients of them for anti-HCV and anti-HGV were determined for HCV-RNA and HGV-RNA by rev erse transcription+nested poly merase chain reaction(RT-PCR).ResultsIn 1 478 patients,the infection rate of HBV was 43.9% (649/1 478),7.9% (117/1 478)patients were positive for HBV-DNA,the infection rate of HCV was 42.6% (630/1 478);the infection rate of HGVwas 46.4% (685/1 478);In 100 positive patients of anti-HCV and anti-HGV, 73% and 77% patients were positive for HCV-RNA and HGV-RNA.ConclusionHepatitis virus infection exists in patients on hemodialysis.It was very important to study risk factors that were related to hepatitis virus.

     

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