Abstract: ObjectiveTo disseminate the acknow ledge about AIDS in young people and to strength their ability of selfprotection and prevention to the AIDS.MethodsBy random group sampling 1 299 students completed the baseline survey about acknowledge and attitude to AIDS,then accepted the intervention by health education about AIDS and efficacy evaluation to it.ResultsBy inter vention of health education,the students.correctrate answering to acknowledge about AIDS significantly increased 3.6% to 54.3% (P<0.01).The intervention indexes are all above 1.ConclusionIt would be very efficatious to disseminate the acknowledge about AIDS in students by health education in colleges.