微量元素与乙型病毒性肝炎关系的研究(1)

Research on Relationship Between Trace Elements and Viral Hepatitis

摘要: 目的探讨微量元素与乙型病毒肝炎的关系.方法用原子吸收分光度计对HBV感染者血清中的微量元素铜、铁、锌、硒进行定,以SPSS9.0forwin进行相应的统计分析.结果 HBV感染者血清Zn低于正常对照组,HBsAg健康携带组血清Se低于对照组.在HBV患者组Cu/Zn、Fe/Zn均高于对照组,具有显着性差异(P<0.01).Logistic回归分析,微量元素Se及Cu/Zn比值进入回归方程.结论微量元素Zn、Se、Cu、Fe与乙型病毒性肝炎存在密切关系.

Abstract: Objective To explore the relationship between trace element and viral hepatitis B.Methods The trace elements contents of Cu、Fe、Zn、Se in sera of patients with HBV was deter mined by spectr ophtometer.The SPSS 9.0 for win was used statistic analysis.Results The serum content of Zn in patients infected with HBV was lower than that of control group.The serum content of Se in patients with HBsAg was lower than that of control group.The value of Cu/Zn,Fe/Zn in patients with HBV were higher than that of control group.The differnece was highly remarkable(P<0.01).Logistic regression analysis demonstred that trace element of Se,Cu/Zn were made way into regression quation.Conclusion The viral hepatis B was related with changes in plasma levels of trace elements.Cu、Zn、Se had close relationship with viral hepatis B.