Objective   To study the effects of buprofezin pro ductin ex posure on the cardiovascular system and the nerve system of occupat ional wor kers.

  Methods   Thirty three wo rkers who exposed to burpofezin and 102 administrators in the of fice in a pestcide factory were selected as the exposure group and control group, respectively.In order to evaluate the exposed levels, the concentration of buprofezin, carbon tetrachlor ide, cholrine in the ambient air of working place in these two groups were monito red simultaneously for theree consecutive days.Moreover, three workers in the exposure group and the control group were selected to evaluate the amount of buprofezin of individual and der mal contamination in three consecutiv e days.Physical examination including the gener al situation, the cardiovascular system(blood pressure, cardiogram), and the nerve system was received according to the standar d method.

  Results   In the ex posure group, the concentrations of buprofezin and carbon tetrachloride were significantly higher than theose in the control group(P < 0.01), while no sig nificant difference of the concentration on chlorine was found(P > 0.05).Furthermore, the concentrations of buprofezin by individual sampling and the dermal contamination detection in the buprofezin exposure area were significantly higher thean those in the control area (P < 0.01).And the abnormality rate of biceps brachii reflection in the exposure group was significantly higher than that in the control group(P < 0.05).

  Conclusion   Occupational exposure to bupr ofezin produciton may affect wor kers nerve system.