下吸呼道感染者不动杆菌ESBLs耐药分析

龙军; 倪艳丽; 樊惠珍

doi:10.11847/zgggws2006-22-04-32

下吸呼道感染者不动杆菌ESBLs耐药分析

Analysis of drug-resistance and examination on Acinotobacter producing extended-specturm β-lactamaes

摘要

摘要:
目的分析引起下呼吸道感染的不动杆菌产超广谱β-内酰胺酶(ESBLs)革兰阴性菌的发生及对10种抗菌药物耐药情况, 并对临床针对性治疗ESBLs耐药菌提出建议。
方法采用全自动微生物分析仪鉴定细菌及用仪器法、双纸片协同试验法、标准纸片扩散确认法对下呼吸道感染标本中分离出的156株不动杆菌作ESBLs的检测, 比较亚胺培南等10种抗菌药物对产ESBLs抗菌作用。
结果产ESBLs耐药株占全部菌株的20.5%, 其中鲍曼不动杆菌占56.2%, 洛菲不动杆菌占25.0%, 溶血不动杆菌占12.5%, 醋酸钙不动杆菌占6.3%。亚胺培南对产ESBLs耐药菌表现出最强抗菌作用。
结论不动杆菌对抗生素已产生多重耐药性, 应注意不动杆菌所致下呼吸道感染。

Abstract:
Objective To analyze occurrence of extended-spectr um B-lactamases(ESBLs)of Acinetobacter isolated from patients with lower respiratory tract infection, and to detect the drug sensitivity to 10 kinds of antibacterial drugs.Finally a suggestion was given to treat lower respiratory tract infection due to A cinetobacter infection.
Methods 156 strains isolated from clinical lower respiratory tract infections specimens were isolated and ESBLs were identified by the VIT EK ESBLs detection test and double-disk synergistic tests and standard disk diffusion test.The effects of 10 kinds of antibacterial drugs to strains were compared.
Results Occurance rate of ESBLs was 20.5%, and pr oductive rate of ESBLs in A.baumanii A.lw of fi, Haemolytius and A.calcoaceticus was 56.2%, 25.0%, 12.5% and 6.3% respectiv ely.
Conclusion Acinetobacter strains isolated form lower respiratory tract infection showed distince antibacterial resistance.Acinetobacter strains producing ESBLs could not be neglected.

HTML全文

参考文献(6)

施引文献

资源附件(0)