Objective   To evaluate the association between serum high-sensitivity C-reactive protein(hs-CRP)and Coronary Heart Disease with Metabolic Syndrome(MS).

  Methods   1326 people who accorded with admitting standardization and date completion were sampled through the chronic diseases investigation from 6 communitys in the resident site of WanZai district.Through collecting fasting blood sample, the concentrations of h-CRP and other biochemical indicator were measured.The difference of h-CRP level between MS and Coronary Heart Disease were compared.

  Results   During 1326 people, 264(19.4%)cases were final diagnosise with MS, 277(20.3%)cases with hypertention, 164(12.0%)cases with Coronary Heart Disease and, 92 cases were Coronary Heart Disease with MS(34.8%).The level of hs-CRP was influenced by age, body weight, smoking, blood lipid and blood glucose.The level of hs-CRP was higher in the patients with hy pertention, Coronary Heart Disease and MS than normal people.the level of hs-CRP was a independent risk factor for MS or hyper tention or coronary heart disease after correcting the risk factors of age, body weight, fasting blood sugar, total cholesterol and trigly ceride.The more the risk factors were, the highter the level of hs-CRP was.

  Conclusion   The level of hs-CRP is a independent risk factor for MS with coronary heart disease and can predict occurring of the coronary heart disease.