Abstract: ObjectiveTo study the pathogenicity and pathogenic condition of ureaplasma urealy ticum(Uu)and mycoplasma homonis(Mh)by mycoplasma infection status between the healthy women and women with genital tractinflammation.MethodTo collect the genital tract secretion in the two groups and detect the infectious ratio and Color Change Unit (CCU)concentration.To study and analyze the mycoplasma infectious status between the two kinds of people by combining with questionnaire data.Results(1)The positive ratio was 84.1% in women with genital inflammation,higher than healthy women whose positive ratio was 55.8% (χ²=26.4571,P<0.0001).(2)Mixed infection of Uu and Mh is popular in infected women.Healthy women are easier to be infected by Uu(χ²=57.2132,P<0.0001).(3)The result of CCU concentration showed the infected concentration in women with genital tractin flammation was higher than healthy women.ConclusionThe patho genicity of Mh is stronger than Uu.The two kinds of mycoplasma have cooperation pathogenic effect.It is easy to lead clinical symptom in the high infectious concentration.So it is meaningful to detect mycoplasma by quantization or half-quantization detection among the infected women and to treat them properly.