Abstract: ObjectiveTo understand the influence factors of the intelligence developmentin adolescence of prematures so as to provide with basis for taking corresponding measures.MethodsThe intelligence quotients(IQ)of 99 junior middle school students born premature were assessed with the Wechsler Intellig ence Scale for Child-Revised Chinese(WISC-RC), then the factors related to intelligence were analyzed using multiple regression model.ResultsUnivariable analysis showed that only-child had higher IQthan not-only-child,older children had lower verbal intellg ence quotients than the younger ones.Family environments factors included parental education attitude and mode.And the related maternal gestational factors included vaginal bleeding in first trimester and second or third trimester,premature rupture of membr anes and mode of delivery.Multiple regression analysis showed that the influence factors forintelligence development were maternal age,father's education background,whether being only-child,parental educational mode and ways of delivery.ConclusionParents should improve family environments and adopt propereducational mode to stimulate the intellgence development of children born premature.