Abstract: Objective To explore the effect of lactochrome and retinol supplementation on pregnant women with iron de ficiency anemia.Methods Anemic pregnant women were divided into four groups and the levels of hemoglobin(Hb),serum ferritin(SF)and serum transferrin receptor(STR)were determined before the trial.According to the doses of the trial,they were seperately supplemented with Fe,Fe+VB₂,Fe+VA and Fe+VB₂+VA.The nutrients were supplemented for 60 days,the levels of hemoglobin,serumferritin and serum transferr in receptor were determined again.Results The levels of Hb were significantly improved after supplementation with Fe,Fe+VB₂,Fe+VA(P<0.05)and Fe+VB₂+VA(P<0.01).The levels of SF in Fe+VB₂+VA group were significantly higher than those in Fe,Fe+VB₂ and Fe+VA groups(P<0.05).The levels of STR in Fe+VB₂+VA group were the lowest of all groups(P<0.05).Conclusion Supplementation with Fe,Fe+VB₂ or Fe+VA respectively could improve the status of anemia,while the effect of improved status of anemia was the best if Fe+VB₂+VA were supplemented at the same time.