Abstract: Objective To know the prevalence of anx iety and depression and it's risk factors among infertile women with the treatment of in vitro fertilization and embryotransfer(IVF-ET),documented for anxiety and depression intervention.Methods A total of 225 infertile women with IVFET were investigated with SA S,CESD,coping style questionnaire and marriage accommodating questionnaire.Results The prevalence of anxiety and depression were 15.6% and 32.0% respectively.With the scores of self-accusation increased,the risk of depression increased.With the scores of problem solving,help-seeking incr eased,the risk of depression decr eased.Marrital years more than 8 years and resident in rural were associated with depression.Infertility time more than 6 years,receiving treatment time at least 3 years,treatment cost over 20 thousands yuan,infertility cause due to women and couples were associated with anxiety.Conclusion Anxiety and depression syndromes are common among infertile women with IVFET.Preventive intervention design should be aimed at related factors of anxiety and depression.