Abstract: Objective To investigate reproduct ive health of females among different g roups in Guangzhou and guide the work on STD/AIDS inter vention.Methods Structured questionnaire was designed.A total of 788 women including three groups(migrants,outpatients from department of gynecology,mid-lowclass FSW)were enrolled to complete a questionnaire after having obtained permission from target people.Blood samples and swabs of vaginal discharge were also collected for detection of STI.Results 788 women were investigated.39.2% of them had the first sex debut under 20 years old;4.1% had more than one partner in the last 3 months.26.8% had ever STD histor y;81.5% of them never used or seldom used condoms.Mig rant females was the least condom-using(13% only)among the three gruops(P<0.05).Pevalence of mid to heavy cervicitis and specific vaginalis were higher in FSW group than that of other two glroups(P<0.001).Females under 25 years old had more than 3 times sex per week and companied with much more abnormal vaginal dischargerate(77% vs 47%,33%)than that of other two groups.Conclusion Bearing-age females' productive condition was not as good as expectation,the age of first sex debut was preceding,low condom using rate,especially,FSW and younger floating females who were all athigh risk to STD/AIDS,were exactly with low-consciousness of sex protection.It is necessary to promote STD/AIDS behavior intervention and health education.