Abstract: Objective To develop and evaluate the reliability of the chronic gastritis scale of the quality of life instruments for chronic diseases(QLICD-CG).Methods Based on the strategy of combination of general model and specific ones,QLICD-CG was developed by the methods of literature review,individual interview and focus group discussion.The scale was used to 1-4 inpatients of chronic gastritis.The reliabilit y of the instrument was assessed by Cronbachαand the test-retest correlation coefficients for each domain and facet.Results The QLICD-CG(V110)was developed with 30 items of general module and 16 items of specific module.The coefficients of internal consistency,split-half and the test-retest reliability of total scores and all domains are as follows:total scores 0.89-,0.733,0.98,physical functioning domain(PHD)0.784,0.851,0.958,psychological functioning domain(PSD)0.878,0.891,0.99,social functioning domain(SOD)0.686,0.678,0.955,the specific module of chronic gastritis(CGD)0.7-8,0.799,0.97.Conclusion The QLICD-CG(V1.0)can be used to assess the quality of life for patients of chronic gastritis with good reliability and reasonable operation in clinical settings.