不同疾病住院患者丙氨酸氨基转移酶水平检测

Retrospective analysis on ALT activities of patients hospitalized in 2007

摘要: 目的探讨住院患者血清丙氨酸氨基转移酶(ALT)不同活性水平在不同脏器、不同疾病中的分布状态,分析血清ALT活性水平对疾病的影响.方法搜集中国医科大学附属第一医院检验科生化组2007年住院患者的ALT检测结果,对其在不同疾病、不同脏器的分布状况进行统计分析.结果 ALT明显增高主要见于肝胆疾病,可占全部肝脏疾病检测结果的15.4%,但ALT活性测定结果多集中分布于40～100U/L,属无症状的ALT升高,并且在各系统疾病中均占50%左右.结论非肝胆疾病住院患者的ALT检测结果中50%以上异常.

Abstract: Objective To analyze the distribution of the activity of ALT in differentorg ans and in patients with different diseases.Methods To collect all ALT test results of the patients(8567 males,5641 females with ages from 0.2 to 90 years old)in the First Affiliated Hospital of China Medical University in 2007 and discuss the distribution status of ALT in different organs.Results Obviously rising of ALT could be found in the diseases of liver and gut,which accounted for 15.4% of the results.However,most results centr alized in the region of 40-100 U/L,accounting for about 50% of the patients with differ ent disease.Conclusion It is weathly to take further research on the reasons of more than a half of the ALT abnormality in hospitalized patients without liver or gut disease.