Abstract: Objective To analyze the correlation beriveen hyperuricem is and non-high density lipoprotein cholesterol (non-HDL-C) and atherogenic index of plasma (AIP) in a noun al population.Methods The 31707 peoplewere studied in a health exam ination from 2004 to 2007.The blood samples from the subjects were detected for uric acid (UA),TC,TCH,HDL and the AIP,non-HDL-C were calculated.Results The concentrations of UA,non-HDL-C for the men was higher than that of the women,and gradually increased with the age Compared with the noun al UA group,the AIP and non-HDL-C were elevated.The UA was positively correlated with the AIP,non-HDL-C and was negatively correlated with the HDL-C.Conclusion The concentration of UA was different among male and female The hyperuricem is population is at high risk of heart and cerebral disease and more attention should be paid to the population.