Abstract: ObjectiveTo study the prevalence of hepatitis Avirus(HAV)and hepa titis Bvirus(HBV)in fection among the rural people of Wuwei area.MethodsA total of 539 people lived in villages and towns were chosen for the study.Anti HAV IgG and HBsAg in serum were detected by ELISA.The prevalence rates of HAV and HBV among the people of different sex,age,education as well as incomes were compared.ResultsThe positive rate of anti HAV IgG (63.08%)in the was subjects lower than the averag level of the whole nation.The positive rate of HBV was 12.08%.There was no difference in anti HAV IgG and HBsAg positive rate among the people of different sex,education and incomes (P>0.05).The positive rate of Anti HAV IgG was higher among the people of 11-20 years old(83.33%)and it was significantly lower among the people of 61-years old(9.09%)than the other age groups(P<0.05).The positive rate of HBsAg was significantly higher among people of 60+years old(24.24%)than the ages of 41-60 years old(P<0.05).ConclusionThe infection rate of HAV among the young people was high and the specific immunity against of HAV in the old people≥60 years was lower and the infection rate of HBV was high among the rural people of Wuwei area.The health education on hepatitis and the vaccination of HAV and HBV need to be promoted.