高血压患者肾素活性、血管紧张素Ⅱ与心电图关系

彭颖; 汪桂艳; 王凌飞; 吴刚; 张显玉; 佟伟军; 张永红

doi:10.11847/zgggws2010-26-03-05

高血压患者肾素活性、血管紧张素Ⅱ与心电图关系

Plasma rennin activity,angiotensin Ⅱ and electrocardiogram manifestation among hypertensives

摘要

摘要: 目的探讨蒙古族人群高血压患者血浆肾素活性(PRA)和血管紧张素Ⅱ(AngⅡ)与缺血性心电图的关系。方法在蒙古族人群高血压现况调查的基础上,对468例高血压患者进行心电图检查、PRA和AngⅡ的检测;采用SPSS 13.0软件进行统计分析。结果缺血性心电图表现组的PRA 1.37 ng/(mL·h)低于非缺血性心电图表现组1.38 ng/(mL·h),但差异无统计学意义(均P>0.05)。缺血性心电图表现组的Ang Ⅱ(51.3 pg/mL)低于非缺血性心电图表现组(53.0 pg/mL),但差异无统计学意义(均P>0.05)。经多因素Logistic回归分析,各PRA和AngⅡ水平对缺血性心电图表现的OR值差异均无统计学意义(均P>0.05)。结论在高血压患者中,PRA和AngⅡ水平与缺血性心电图表现均无关联。

Abstract: Objective To explore the relationship bewteen plasma rennin activity(PRA),angiotensin Ⅱ(Ang Ⅱ)and ischemic electrocardiogram manifestation(IEM)among hyperten sives.Methods Based on a cross sectional study on hyperten sion,electro cardio gram examination was conducted amonga Monglian population.PRA and Ang Ⅱ were tested for 468 patients with hyperten sion.SPSS 13.0 sofwtare was used to analyze the data.Results There was no significant difference in PRA and Ang Ⅱ levels between subjects with IEM and normal EM(PRA:1.37 vs 1.38 ng/mL·h;Ang Ⅱ:51.3 vs 53.0 pg/mL,P>0.05).The multivariate logistic analysis showed that the oddsratios of PRA and Ang Ⅱ levels for IEM were not significant(P>0.05)among the subjects.Conclusion The levels of PRA and Ang Ⅱ are not associated with IEM among patients with hypertension.

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