Abstract: Objective To explore the risk factors of hypemricemia for the prevention and cotroll of the disorder.Methods A cross-sectional survey was conducted among 1 965 m fiddle-aged and older residents and logistic regression was used to analyze the risk factors of hyperuricem is.Results The adjusted prevalence rate of the hyperuricem is in the middle and old age residents was 17.7% and there was a significant difference in the prevalence between themale and femalepar ticipans The multivariate logistic stepwise regression analysis showed that the stagle food intakes (OR=0.76) was benefit to hyperuricem is prevention.But high blood pressure (OR=2.79),body mass index (BMI) (OR=1.19),age (OR=1.08), and the intake of aquatic product (OR=1.87)were risk factors for hypemricemia.The overweight (OR=2.29,95CI:1.76-2.98) and obesity (OR=4.56, 95CI:3.12-6.66) were associated with hyperuricem is after adjusted for age, blood pressure and gender.The hypertensive(OR=1.63, 95CI:1.21-10.95) had a higher risk of the hypemricem is compared with the participans without hypertention.The residents with both obesity and hypertention had a much higher risk of hyperuricemia (OR=6.52,95%CI=3.88-10.95) compared with the residents with noonal body weight and blood pressure.Conclusion hyperten sion, obesity and their combined effect were associated with hyperuricemia.