天津市地氟病重病区流行病学特征分析
Prevalence of endemic fluorosis in heavily prevalent area of Tianjin
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摘要: 目的 了解天津市地氟病重病区的流行现状。方法 根据地氟病重病区的分布特点,选取3个重病区,每个重病区按照整群抽样的方法抽取调查点,每个调查点测定水氟、8~12岁儿童氟斑牙、尿氟及对16岁~人群氟骨症患者进行临床检查和X线检查。结果 在8个调查村中,儿童尿氟中位数为2.64 mg/L,女童尿氟高于男童,不同年龄儿童尿氟差异无统计学意义;水氟与尿氟之间呈高度正相关;14个调查村中儿童氟斑牙检出率为81.1%,不同性别儿童氟斑牙分度差异无统计学意义;但随年龄的增加氟斑牙分度增加,饮水氟含量与氟斑牙分度呈正相关;临床氟骨症检出率为29.2%,X线检查氟骨症阳性率为39.4%,不同性别间氟骨症差异无统计学意义,但不同年龄间氟骨症差异有统计学意义。结论 天津市地氟病重病区病情依然较重,水氟越高儿童氟斑牙、成人氟骨症越严重,年龄越大成人氟骨症越严重。Abstract: Objective To investigate epidemiologic characteristics of endemic fluorosis in heavily prevalant area of Tianjin.Methods Three endemic fluorosis prvalence areas were selected with cluster sampling.The content of water fluoride,dental fluorosis among children aged 8-12 years,the situation of ske letal fluorosis among people above 16 years old,and the concentration of urine fluoride were detected.Results The geometric mean of urine fluoride was 2.64 mg/L.The urine fluoride of the girls was higher than that of the boys.The urine fluoride was positively correlated with water fluoride.The averag erate of dental fluorosis was 81.1%.The rate of dental fluorosis increased with age and positively corre lated with water fluoride.The prevalence rate of clinic skeletal fluorosis was 29.2% and the Xray positive rate was 39.4%.Conclusion The endemic fluorosis is still very serious in heavily prevalent areas of Tianjin.The prev alence rate of children dental fluorosis and adult skeletal fluorosis are positively correlated with water fluoride.The prev alence rate of adult skeletal fluorosis increases with age.
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