Abstract: Objective To investigate the status and influencing factors of knowledge about folic acid among people in Xi'ning city and to provide evidence and measures for health education on folic acid.Methods Totally 492 local people were surveyed.Univariate analysis and logistic regression were used to explore the influencing factors.Results The general rate of awareness of folic acid was 30.4%.There were 22.7% of the people knowing some diseases are related to deficient folic acid in daily dietary,11.4% knowing the folic acid could be lost in daily cookings,24.2% knowing smoking and drinking could influence absorption of folic acid,and 38.5% knowing some foods and fruits contain folic acid.Multiple unconditional logistic regression analyses indicated that female and married were risk factors and with eduation of middle school or higher and living in urban area were protective factors for knowledge level of folic acid.Conclusion The knowlegde rate of folic acid is low and gender,education level,residential place,and marriage status are major factors influencing the knowledge rate among the residents of Xi'ning city.