Abstract: Objective To investigate the intake of salt iodine and the prevalence of thyroid nodule in the population with different levels of iodine nutrition and to provid the basis for scientific iodine supplementation.Methods The level of urinary iodine was measured with spectrophotometer method; the iodine in table salt was measured with sodium subsulfite method; the thyroid nodule was detected by Brightness mode.Results Totally 1 057 inhbitants randomly selected from 13 counties were investigated.The medians of urinary iodine for the inhabitants with adequate,above requirement,and excessive iodine nutrition were 149.06,256.12,and 275.60 μg/d,respectively.The levels of urinary iodine increased with iodine intake.The prevalence of thyroid nodule in the populations with adeguate,above requirement,and exessive iodine nutriton were 14.47% (66/456),14.95% (48/321),and 21.07% (59/280),indicating that the detection rate of thyroid nodule increased with the iodine intake.Conclusion When the iodine intake is within the appropriate level proposed by WHO,the thyroid nodule detection rate is at a low level.