Abstract: ObjectiveTo evaluate the effect of health education and behavioral intervention on AIDS control among female sex workers(FSWs),and to provide reference for making human immunodeficiency vivus(HIV)prevention and intervention measures.MethodsContinuous surveillance was conducted among FSWs from 2005 to 2012.SPSS13.0 was used in data analyses.ResultsThe awareness rate of related knowledge about AIDS was increased from 61.3% in 2005 to 88.6% in 2012.The rate of condom use in the last commercial sexual intercourse was raised from 57.5% in 2005 to 91.6% in 2012,and the rate of consistent condom use during the last month was raised from 42.4% to 75.9%.The rate of HIV test was increased from 9.4% to 51.4%.The results of logistic regression showed that minority,low education,marriage status of cohabitation and divorce were influential factors of condom use.ConclusionComprehensive health education and behavioral intervention are effective among FSWs in Gansu province,but more concerns should be paid to the FSWs with low education or with marriage status of cohabitation,divorce or windowed.