Abstract: Objective To study the quality of life(QOL)and its influential factors among migrant elderly population in Guangdong province.Methods Medical Outcomes Study 36-Item Short-From Health Survey(SF-36)Chinese version was employed in the survey.The study sample consisted of 257 migrant elderly persons from 9 cities.Results The QOL score of the elderly was 79.67±17.35 for physical functioning,60.21±40.33 for physical role,65.65±21.28 for bodily pain,55.93±17.04 for general health,69.12±16.78 for vitality,79.96±39.40 for social functioning,55.25±44.87 for emotional role,and 75.63±16.07 for mental health,respectively.Multivariable analysis showed that gender(β=-1.204,P=0.000),age(β=-0.781,P=0.028),smoking(β=1.346,P=0.000),sleeping(β=2.217,P=0.019),cultural level(β=1.639,P=0.001),physical condition(β=-2.295,P=0.000),and chronic disease(β=0.979,P=0.002)significantly influenced the quality of life among migrant elderly population.Conclusion Gender,age,smoking,sleeping,education level,physical condition,chronic disease are major factors influencing the quality of life of migrant elderly population.