Abstract: Objective To examine the prevalence of drinking driving around an entertainment area(Number 1912 Block Area)in Nanjing city and to provide basis for intervention on drinking driving.Methods A cross-sectional survey was conducted on the roads around Number 1912 Block Area and a total of 1 063 randomly recruicted drivers were interviewed with a questionnaire after performing a roadside breath testing.Results The incidence of drinking driving(with the blood alcohol concentration of >0 mg/100 ml)was 3.57%;the incidence of driving under the influence of alcohol(DUI)(with the BAC of ≥20 mg/100 ml but <80 mg/100 ml)was 2.45% and the incidence of driving while intoxicated(DWI)(with the BAC of ≥80 mg/100 ml)was 0.47%.The drivers were more likely to drink alcohol after midnight(6.05%)than before midnight(0.43%)(χ²=24.029, P<0.001).The incidence of drinking driving in motorcyclists(23.08%)were higher than that of in other drivers(3.09%)(χ²=23.893, P<0.001).The incidence of drinking driving for drivers aged 18 to 30, 31 to 50 and 51 to 69 years were 5.10%, 2.49% and 1.16%, respectively.The incidence of drinking driving for drivers who did buckle up/wore helmets and those who did not take safety measures were 3.00% and 9.38%.The differences in the incidence of drinking driving among different groups of drivers were significant(all P<0.05).Conclusion The incidence of drinking driving was high around entertainment areas in Nanjing city, and the incidence was different at different times and among the driver groups driving different type of vehicles, at various age, and whether taking safe-driving measures.