孕早期家用化学品使用与妊娠结局关系

俞洋; 郝加虎; 黄锟; 苏普玉; 陶芳标; 童世庐

doi:10.11847/zgggws2014-30-09-08

孕早期家用化学品使用与妊娠结局关系

doi: 10.11847/zgggws2014-30-09-08

俞洋^1,2,
郝加虎^1,2,
黄锟^1,2,
苏普玉^1,2,
陶芳标^1,2, ,,
童世庐^1,3, ,

1.
安徽医科大学儿少卫生与妇幼保健学系, 安徽合肥 230032;
2.
安徽人口健康与优生省级实验室;
3.
澳大利亚昆士兰理工大学公共卫生和生物医学创新研究所

基金项目:

国家十一五科技支撑计划（2006BAI05A03）

详细信息

作者简介:
俞洋（1988- ），男，安徽六安人，硕士在读，研究方向：环境与人口健康。

通讯作者:
童世庐，s.tong@qut.edu.au;陶芳标，fbtao@126.com

童世庐，s.tong@qut.edu.au;陶芳标，fbtao@126.com

中图分类号: R181.3
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出版历程
- 收稿日期: 2013-11-18
- 刊出日期: 2014-09-10

Association of household chemical use during first trimester pregnancy with risks of adverse birth outcomes

1.
Department of Child and Adolescent Health and Maternal and Child Health, School of Public Health, Anhui Medical University, Hefei, Anhui Province 230032, China

摘要

摘要: 目的探讨孕早期家用化学品使用与3种不良妊娠结局（早产、低出生体重、小于胎龄儿）的关联情况。方法选取在安徽省合肥、芜湖、马鞍山市妇幼保健部门进行孕产期保健体检并分娩单胎活产儿的10 269名育龄妇女为研究对象，分析不同特征育龄妇女孕早期家用化学品使用情况与不良妊娠结局关系。结果美白霜的使用频率最高，其他家用化学品的使用频率较低，6 827人（66.5%）表示几乎不使用除美白霜以外的家用化学品；调查对象早产、低出生体重、小于胎龄儿发生率分别为3.4%、1.8%、3.2%；以几乎不用为对照组，二项logistic回归结果显示，家用化学品使用与低出生体重（RR=1.11，95%CI=0.83～1.49）、小于胎龄儿之间（RR=1.07，95%CI=0.85～1.33）无统计学关联，甚至在早产组呈现出一种保护效应（RR=0.73，95%CI=0.58～0.91）。结论育龄妇女孕早期家用化学品使用与3种不良妊娠结局不存在关联。
- 家用化学品 /
- 早产 /
- 低出生体重 /
- 小于胎龄儿
Abstract: Objective To investigate effects of household chemical use during first trimester of pregnancy on adverse birth outcomes,including preterm birth(PB),low birth weight(LBW),and small for gestational age(SGA).Methods A total of 10 269 women of childbearing age who gave birth to single and live babies were recruited from October 2008 to October 2010 in 3 maternal and child health centers in Hefei,Wuhu,and Maanshan city.Chi-square test and binary logistic regression were used to analyze the association between household chemical use and adverse birth outcomes.Results Among the women,whitening cream was most frequently used during the first trimester,while the other household chemicals were rarely used.The incidence of PB,LBW,and SGA were 3.4%(343/10 120),1.8%(183/10 186),and 3.2%(324/10 091),respectively.The adjusted relative risks of PB,LBW,and SGA related to household chemical use were 0.73(95% confidence interval[95%CI]:0.58-0.91),1.11(95%CI:0.83-1.49),and 1.07(95%CI:0.85-1.33),respectively.Conclusion Overall,the results of the study did not suggest an association between household chemical use of pregnant women during the first trimester and adverse birth outcomes.
- household chemical /
- preterm birth /
- low birth weight /
- small for gestational age

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参考文献(15)

[1]	陈涛,黄红,田英.室内、外环境因素与儿童白血病关系的研究进展[J].环境与职业医学,2009,26(1):89-92.
[2]	俞洋,郝加虎,黄锟,等.安徽省妇女孕前家用化学品使用情况及影响因素[J].环境与健康杂志,2013,30(9):786-789.
[3]	Chou WC,Chen JL,Lin CF,et al.Biomonitoring of bisphenol A concentrations in maternal and umbilical cord blood in regard to birth outcomes and adipokine expression:a birth cohort study in Taiwan[J].Environ Health,2011,10(94),PMID:22050967.doi: 10.1186/1476-069X-10-94.
[4]	Al-Saleh I,Shinwari N,Mashhour A,et al.Birth outcome measures and maternal exposure to heavy metals (lead,cadmium and mercury) in Saudi Arabian population[J].Int J Hyg Environ Health,2014,217(2-3):205-218.doi: 10.1016/j.ijheh.2013.04.009.
[5]	Goldenberg RL,Culhane JF,lams JD,et al.Epidemiology and causes of preterm birth[J].Lancet,2008,371(9606):75-84.
[6]	Chen Y,Li G,Ruan Y,et al.An epidemiological survey on low birth weight infants in China and analysis of outcomes of full-term low birth weight infants[J].BMC Pregnancy and Childbirth,2013,13(1):242.
[7]	徐蓉,郝加虎,陶芳标,等.10407名单胎活产儿SGA发生率及其影响因素的队列研究[J].中国妇幼保健,2012,27(4):560-565.
[8]	Zhang CY,Jiang Y,Yin QY,et al.Impact of nurse-initiated preoperative education on postoperative anxiety symptoms and complications after coronary artery bypass grafting[J].J Cardiovasc Nurs,2012,27(1):84-88.
[9]	Gong X,Hao J,Tao F,et al.Pregnancy loss and anxiety and depression during subsequent pregnancies:data from the C-ABC study[J].Eur J Obstet Gynecol Reprod Biol,2013,166(1):30-36.
[10]	Ronda E,Moen BE,Garca AM,et al.Pregnancy outcomes in female hairdressers[J].Int Arch Occup Environ Health,2010,83(8):945-951.
[11]	Herdt-Losavio ML,Lin S,Druschel CM,et al.A nested case-control study of low birth weight among cosmetologists[J].Int Arch Occup Environ Health,2011,84(6):601-608.
[12]	Herdt-Losavio ML,Lin S,Druschel CM,et al.The risk of having a low birth weight or preterm infant among cosmetologists in New York State[J].Matern Child Health J,2009,13(1):90-97.
[13]	Halliday-Bell JA,Gissler M,Jaakkola JJ.Work as a hairdresser and cosmetologist and adverse pregnancy outcomes[J].Occup Med,2009,59(3):180-184.
[14]	Van Engelen JG,Heinemeyer G,Rodriguez C.Consumer exposure scenarios:development,challenges and possible solutions[J].J Expo Sci Environ Epidemiol,2007,17(suppl 1):S26-33.
[15]	Cowan-Ellsberry CE,Robinson SH.Refining aggregate exposure:example using parabens[J].Regul Toxicol Pharmacol,2009,55(3):321-329.

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孕早期家用化学品使用与妊娠结局关系

doi: 10.11847/zgggws2014-30-09-08

作者简介:
俞洋（1988- ），男，安徽六安人，硕士在读，研究方向：环境与人口健康。

通讯作者:
童世庐，s.tong@qut.edu.au;陶芳标，fbtao@126.com

童世庐，s.tong@qut.edu.au;陶芳标，fbtao@126.com

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Association of household chemical use during first trimester pregnancy with risks of adverse birth outcomes

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目录

留言板

孕早期家用化学品使用与妊娠结局关系

doi: 10.11847/zgggws2014-30-09-08

作者简介: 俞洋（1988- ），男，安徽六安人，硕士在读，研究方向：环境与人口健康。

通讯作者: 童世庐，s.tong@qut.edu.au;陶芳标，fbtao@126.com 童世庐，s.tong@qut.edu.au;陶芳标，fbtao@126.com

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出版历程

Association of household chemical use during first trimester pregnancy with risks of adverse birth outcomes

计量

出版历程

目录

作者简介:
俞洋（1988- ），男，安徽六安人，硕士在读，研究方向：环境与人口健康。

通讯作者:
童世庐，s.tong@qut.edu.au;陶芳标，fbtao@126.com

童世庐，s.tong@qut.edu.au;陶芳标，fbtao@126.com