Abstract: Objective To explore the correlation between post-traumatic stress disorder(PTSD) and sleep disorder among 708 patients from 8 hospitals in Pearl River Delta,and to analyze influence factors of sleep quality among PTSD patients.Methods With target sampling,708 patients were chosen from 8 grade two hospitals in Pearl River Delta for a self-administrated anonymous questionnaire survey with PTSD Checklist-Civilian Version(PCL-C) and Pittsburgh Sleep Quality Index(PSQI) under the help of investigators.Results Among the patients,the overall prevalence of PTSD symptoms was 27.5%,with the proportion of 31.8%(62/195) for severe symptoms and 68.2%(133/195)for mild to moderate symptoms.The prevalences of sleeping problem were 37.9% for all the patients,27.9%(143/513) for the patients without PTSD symptoms,and 57.9%(77/133) and 77.4%(48/62)for the patients with mild or moderate and severe PTSD symptoms,respectively.The average PSQI score was 6.79±3.78 among the 513 patients without PTSD symptoms,with 143 patients having sleeping disorder; whereas,the score was 6.62±3.69 and 7.26±3.72 among 133 patients with mild or moderate PTSD symptoms(77 having sleeping disorder) and 62 patients with severe PTSD symptoms(48 having sleeping disorder).There was a positive correlation between PCL-C and PSQI(r=0.480,P<0.05).There were significant differences in the general sleeping status and the 7 sleeping-related factors among the patients with different severity of PTSD symptoms.Multi-factor analyses showed that the main influence factors of sleep disorder for PTSD patients were the duration from the time of the accident(odds ratioOR=1.303,95% confidence interval95%CI=1.129-1.503; P=1.303),spinal injury(OR=1.991,95%CI=1.219-3.251; P=0.006) and ability of self-care(OR=1.684,95%CI=1.286-2.206; P=0.000).Conclusion PTSD and sleep disorder have a positive correlation.Patients with different severity of PTSD could have different performance in term of sleep disorder and the duration from the time of the accident,spine injury,and ability of self-care were main influencing factors for sleep disorder in PTSD patients.