Abstract: ObjectiveTo explore the relationship between occupational stress and depression symptoms in different occupational populations.MethodsWith stratified sampling,1 819 persons with different occupations were recruited for a self-administered questionnaire survey in Yili region of Xinjiang Uygur Autonomous Region(Xinjiang).Occupational Stress Inventory-Revised Edition(OSI-R)was used to measure job strain and Self-Rating Depression Scale (SDS) was used to assess depressive symptoms.Information on sociodemographic characteristics and individual life behaviors were also collected.Logistic regression analysis was used to determine the associations between depressive symptoms and occupational stress factors.ResultsAmong the participants,the average SDS score was 37.69±11.35 and the prevalence of depressive symptoms was 18.5%.Multivariate logistic regression revealed the risk factors of depressive symptoms included work maladjustment,body tension response,and psychological stress reaction,with the odds ratios(ORs)and their 95% confidence interval(95CI%)of 1.59(95CI% :1.11-2.28),1.60(95CI% :1.13-2.26),and 1.49(95CI% :1.03-2.15)and the protective factors included smoking,high social support,and high rational coping,with the ORs and their 95CI% of 0.37(95CI% :0.25-0.54),0.80(95CI% :0.58-0.90),0.65(95CI% :0.49-2.15),respectively.ConclusionDemographic characteristics,individual life behaviors,and work stressors are influencing factors for depressive symptoms among different occupational populations in Xinjiang.