Abstract: Objective To examine the status of sleep quality and the prevalence of depressive symptoms and to explore the correlation between sleep quality and depressive symptoms among middle school students in Shenzhen city.Methods Totally 3 168 students were randomly selected from 12 middle schools in Shenzhen city using a two-stage stratified cluster sampling and were surveyed anonymously with Pittsburgh Sleep Quality Index (PSQI) and Depression Self-Rating Scale for Children (DSRSC) between October 2015 and January 2016.Results The average total PSQI score of the students was 5.41±2.93 and 22.0% of the students were identified with poor sleep quality.The mean DSRSC score of the students was 8.39±6.09 and 17.0% of the students reported depressive symptoms.A positive correlation between total PSQI score and DSRSC score (r=0.443,P<0.001) was observed among the students.Conclusion Poor sleep quality and depressive symptoms are prevalent,to some degree,and the two disorders are positively correlated among middle school students in Shenzhen city.