女用安全套预防性传播疾病的效果评价

姜宝法; 郭秀英; 付萍; 徐晓菲; MacalusoMaurizio

女用安全套预防性传播疾病的效果评价

Efficacy of female condom for prevention of sexually transmitted diseases

摘要

摘要:
目的评价女用安全套防止非意愿性妊娠和性传播疾病的效果.
方法以40名健康育龄妇女志愿者为研究对象, 每人使用5个女用安全套, 每次使用前、后各采集阴道分泌物标本, 记录安全套出现机械性问题的情况, 采用化学发光免疫测定法检测标本浸泡液中前列腺特异性抗原(PSA)浓度.
结果 .186个安全套中有1827%至少出现1次机械性问题; 自我报告有机械性问题者的后拭子PSA平均浓度为(33.35±35.56)ng/ml, 无机械性问题者的后拭子PSA平均浓度为(14.97±16.96)ng/ml, 二者有显著性差异(t=8942, P < 0.001);有机械性问题与PSA阳性密切相关(r=0.77, P < 0.001).
结论尽管使用屏障性避孕工具可以有效地防止性病/艾滋病的传播, 但根本的预防方法还是洁身自好, 避免婚外不洁性行为.

Abstract:
Objective To evaluate the efficacy of female condom for preventing sexually transmitted diseases.
Methods 40 healthy married women were recruited as volunteers to participate the study, 5 female condoms were used for each woman, pre-and post-coital vaginal swabs, a completed form describing problems that occurred during condom use were collected.Prostate-specific antigen(PSA)in the luents of the vaginal swab was tested with the chemiluminescent immuno assay.
Results At least one mechanical problem was experienced in 18.27% of used condom.The post-coital PSA mean level with the self-reported problem was(33.35±35.6)ng/ml, and it was(14.97±16.96)ng/ml without self-reported problem.there was a significant statistical difference(t=8.942, P < 0.001);and also a significant correlation between mechanical problem and PSA level(r=0.77, P < 0.001).
Conclusion Although female condom could prevent the infection of STD and HIV, the radical method of preventing STD and HIV was to avoid having sex with the person other than spouse.

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