5km重复低压缺氧对小鼠肝脏及脾脏中微量元素的影响

贾镭; 高梅; 马洪波; 王咏梅; 杨中万; 王长文; 宋春梅

5km重复低压缺氧对小鼠肝脏及脾脏中微量元素的影响

Influence of 5km reiteration hypobaric hypoxia on content of trace elements in mice's livers and spleens

摘要

摘要:
目的探讨5km重复低压缺氧对小鼠肝脏及脾脏中微量元素的影响.
方法将小白鼠分为5km重复低压缺氧实验组及地面对照组.实验组每天进行5km重复低压缺氧30min, 连续7d后, 处死小鼠, 取肝脏、脾脏烘干至恒重, 采用火焰原子吸收法测定锌、铜、铁.
结果 5km重复低压缺氧小鼠肝脏中Cu、Fe含量与对照组比较有显著差异(P < 0.05);脾脏中微量元素Fe的含量与对照组比较有显著性差异(P < 0.05).
结论 5km重复低压缺氧, 使肝脏中Fe、Cu含量降低, 脾脏中Fe含量升高.

Abstract:
Objective To probe into the influence of 5 km reiteration hypobaric hypoxia on the content trace elements in mice's livers and spleens.
Methods Mice were divided into two groups, group of 5 km hypobaric hypoxia for 30 min and ground control group.In experimental group the mice were exposed to 5 km hypobaric hypoxia for 30 min and successive for 7 d.At the eighth day mice were executed, and livers and spleens were taken to dry to eternal weight.Atomic absorption spectrophotometry was used to detect the contents of Zn, Fe, Cu in livers and spleens of mice.
Results The contents of Cu, Fe in mice's livers at group of 5 km reiteration hypobaric hypoxia had significant difference compared with the control group(P < 0.05).So did the content of Fe in mice's spleens(P < 0.05).
Conclusion 5 km reiteration hypobaric hypoxia caused the contents of Fe, Cu in mice's livers decreased, the content of Fe in mice's spleen increased.

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