锰对接触男工性激素的影响

Effects of Manganese Exposure on Male Sexual Hounone

摘要: 为评价锰接触对下丘脑-垂体-性腺轴的影响，选择健康男工112人，其中锰接触男工58名（血锰2.13±0.95mol/L）,非接触男工54名（血锰1.49±0.59mol/L）,以放射免疫法测定其血清FSH、LH及睾酮。接触组平均血清睾酮浓度为21.94nmol/L,明显低于对照组的27.97nmol/L,而血清LH水平4.02IU/L,明显高于对照组的3.29IU/L;两组工人血清FSH含量差异无显着性，分别为5.53和5.76IU/L.提示男工接触锰后，可影响下丘脑-垂体-睾丸分泌功能，引起血清睾酮和LH浓度的改变。

Abstract: To evaluate the effects of manganese exposure on hypothalam ic-Pituitary-testicularax is function,blood samples were collected from 122male workers,among them 58 workers exposed to manganese occpuationally.